The two objectives of this study are: 1) validation of two questionnaires, the Misophonia Screening List - Child and Youth and the Amsterdam Misophonia Scale-Youth (AMISOS-Y), in order to screen adequately for misophonia 2) testing the…
ID
Source
Brief title
Condition
- Psychiatric disorders NEC
Synonym
Health condition
Misophonia is a recently identified disorder in which individuals experience intense, uncontrollable and disproportional irritation, anger or disgust when confronted with specific sounds or stimuli associated with these sounds.
Research involving
Sponsors and support
Intervention
- Other intervention
Outcome measures
Primary outcome
Severity of misophonia symptoms (AMISOS-Y)
Secondary outcome
- Misophonia complaints (Misophonia Screening List - Child and Youth) - Psychopathology in the child (attention and concentration problems, anxiety/depression, oppositional behavior, compulsions) - Severity of psychopathology (change over time) - School functioning - Quality of life - Attention problems - Sensory processing - Care related quality of life - Cost of illness - Social validity of treatment - Family accommodation to misophonia - Coercive disruptive behavior child
Background summary
Internationally, very little research has been conducted into symptoms of misophonia. The disorder misophonia was first described worldwide by Prof. Denys of the Amsterdam UMC. This is special, because it is very rare that a new psychiatric disorder is discovered. Some research has already been carried out in adults, but very little is known about misophonia in children / adolescents. People suffering from misophonia are overcome by uncontrollable, extreme anger, disgust or hatred at hearing normal human sounds (such as chewing, smacking, nose sniffing, or breathing) especially in the home setting. This can also occur when seeing movements that arouse the feelings (e.g. grinding jaw). Epidemiological studies on misophonia in children have not yet been performed. Two studies among young students show that the prevalence of clinically significant misophonia symptoms varies from 6% -20%. Research at the psychiatry outpatient clinic of the Amsterdam UMC, location AMC, in nearly 600 adult patients with misophonia, has shown that the average age of onset is around 13 years, so the complaints develop at a young age. Children are regularly referred to de Bascule/Levvel from the age of 8, whilst they have been suffering already for several years. Although many adults and children can experience these misophonia symptoms in a mild form, for some they mean tremendous suffering. The strong emotions and negative thoughts must always be suppressed, which is very tiring. Misophonia can have a serious disruptive impact on children's lives, at home, at school and within the family. For example, children can no longer eat, sleep, drive a car (e.g. while on vacation) or lead a normal family life with the family. There is a lot of avoidance and anticipation of fear of situations with the sounds. Thusfar, Dutch questionnaires for the screening and diagnostics of misophonia in children and adolescents have not been validated yet. Furthermore, there is no evidence-based treatment protocol.
Study objective
The two objectives of this study are:
1) validation of two questionnaires, the Misophonia Screening List - Child and Youth and the Amsterdam Misophonia Scale-Youth (AMISOS-Y), in order to screen adequately for misophonia
2) testing the effectiveness of an innovative treatment protocol for misophonia in children and adolescents
Study design
3 time points:
- T1 Baseline measurement (start)
- T2 3 months after T1
- T3 6 months after T1
Intervention
Group treatment, consisting of a combination of CBT and PMT
Age
Inclusion criteria
Patients between the ages of 8 and 18 years old who are referred to the Amsterdam
UMC/Levvel for the diagnosis and treatment of misophonia, who are in need of treatment
according to the clinician, parents, and/or themselves, and who do not have comorbid
symptoms or diagnoses that might hinder treatment protocol adherence, are eligible for
participation in the study. Children above the age of 12 and their parents need to provide
informed consent.
Exclusion criteria
Ineligible are children who:
- have another primary diagnosis than misophonia (e.g. ADHD)
- have psychiatric comorbid symptoms or diagnoses that hinder group functioning (e.g. severe autism)
- have psychiatric comorbid symptoms or diagnoses requiring adjustment of the misophonia treatment protocol (e.g. severe autism)
- have received cognitive behavioral therapy for misophonia in the past year
- display self-injurious behavior (i.e. auto-mutilation) at present or in the past year
- have an estimated IQ below 85
- are unable to read or write Dutch
- have serious family problems (e.g. divorcing parents) that hinder group functioning or would require adjustment of the misophonia treatment protocol
Design
Recruitment
IPD sharing statement
Plan description
Kamer G4-214
Postbus 22660
1100 DD Amsterdam
020 566 7389
mecamc@amsterdamumc.nl
Followed up by the following (possibly more current) registration
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
| Register | ID |
|---|---|
| NTR-new | NL9724 |
| CCMO | NL76129.018.21 |
| OMON | NL-OMON52247 |