826 results
To asses the effectiveness of surgery 7 and 10 years after conventional vaginal POP surgery compared with tension free vaginal mesh.
Primary Objective: The aim of this study is to determine a cut-off score at the PQ-16 with the CAARMS for better detection of adolescents 12-18 years at risk. Secondary Objective(s): To study the course of UHR in adolescents 12-18 years over a one…
The overall aim of the study is to improve diagnostic and therapeutic options for people with CF, especially in the context of young children and novel CFTR-targeting drugs. Primary Objective: 1. to demonstrate relations between CFTR genotype,…
The primary objective is to obtain OCT data for children aged 4 to 10 diagnosed with non-syndromic craniosynostosis and to compare these to the normal reference values.
Primary:To determine the prevalence of pruritis in patients with hidradenitis suppurativa.Secondary:- to evaluate pruritis severity and its effect on three elements of daily activities;- to evaluate differences in extensiveness of HS in relation to…
The primary objective of this study is to identify in which imaging modality, including CE and vortex imaging, could help us in the early diagnoses of intracardiac thrombosis in LVAD patients. We attempt to provide a more dedicated method for the…
The aim of the basic research in the laboratory is to develop new treatments to repair large bone defects, repair cartilage defects or inhibit the progression of osteoarthritis (cartilage degeneration). We focus on the following questions:1.How can…
To compare the tidal volume distribution and other ventilator parameters between PAV+ and NAVA.
1. To validate accelerometer cut-points to asses physical activity and sedentary behavior of breast cancer survivors. 2. To investigate the validity of accelerometers, inclinometers, heart rate and oxygen consumption to assess time spent in…
The assumptions of the traumatic effects of coercive measures as described in the literature will be examined in the present study. The research questions are how coercive measures are experienced by patients, to what extent these measures are…
The proposed study will further examine the effects of pregnancy on the human brain, by investigating structural and functional connectivity, local metabolite concentrations and neural activity related to social cognitive and memory processes.…
Primary Objective:First we need to establish that patients with an eating disorder and healthy controls differ in mental imagery. So, the first aim of our research is to compare the nature and characteristics (emotionality, vividness and perspective…
To investigate whether bright light therapy is an effective treatment for depression during pregnancy compared with low-intensity placebo light therapy (proof-of-principle) and to investigate the late effects of bright light therapy versus placebo…
The primary objective of this study is to assess reasonable safety and performance of the HeartMate PHP to provide hemodynamic support for up to 72 hours in patients with cardiogenic shock requiring stabilization.
The first objective is to assess the value of colonoscopy screening in HL survivors. The second objectives are to evaluate the neoplasia characteristics and its relation to radiotherapy and chemotherapy, in order to improve the understanding of the…
Monitoring and evaluation of the Dutch guideline for treatment of aHUS in children and adults during two years.
Objective 1: To collect information on risk factors and biomarkers in a screening cohort, develop a tailor-made risk prediction model and, subsequently, model the impact of adapting breast cancer screening policy to populations at varying levels of…
This study aims to investigate the process and outcome of the implementation of a coaching intervention in COPD care in the Friesland province.
Therefore, the aim of the myAirCoach project is to develop and evaluate technologies that assist patients with asthma. To this purpose we developed a one year observational quantification campaign in which we will identify potentially relevant self-…
- To determine whether there is a mitigated immediate immune response to islet infusion in immunosuppressed recipients- To determine if complement activation during immediate immune response is affected in immunocompromised recipients