1407 results
To assess the provoking effect of partial sleep deprivation on paroxysmal neurological events in a EMU setting, in people with possible epileptic seizures.
Primary Objectives: * To determine if NA patients have altered cerebral activity related to motor planning of their affected arm compared to healthy controls and compared to their non-affected arm.* To determine if specific rehabilitation focused on…
The primary objective of this study is to analyse the microenvironment of the primary tumour and sentinel and non-sentinel lymph node(s) (i.e. various T-cell populations, antigen presenting cells and myeloid-derived suppressor cells) in patients…
1.1 Overall Aim: To establish a safe, standardized protocol for the perioperative management of patients with atrial fibrillation (AF) who are receiving a novel oral anticoagulant (NOAC) drug, either dabigatran, rivaroxaban or apixaban, and require…
1) To evaluate changes in microvascular resistance of the infarcted area in the first hours after ST-elevation myocardial infarction and during the recovery period (<5 days)2) To classify patients according to recovery of microvascular…
- To compare relative myocardial mass distribution (i.e. mass of the respective territories of LAD, LCX and RCA) by CT scanning to normalized hyperemic blood flow in the three major myocardial territories as assessed by absolute flow measurements…
To study the effect size of FMT after a 3 weeks course of budesonide as induction therapy in patients with active ulcerative colitis despite previous therapy. The purpose of the pre-treatment is to reduce active inflammation prior to donor feces…
Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.
Objective: The primary objective of this study is to investigate whether pain experience decreases or increases when cognitive functions decline in patients with Parkinson's disease. Furthermore will be investigated whether this is influenced…
Measuring cardiac output using TTE with and without the use of ProbeFix in adult Intensive Care patients in which a PLR test is used as a fluid challenge. The possible changes in cardiac output measured with TTE are compared with the measurements…
The primary objective for this trial is to assess the local cancer control achieved with FLA in patients with localized low to intermediate risk prostate cancer (Gleason 3+3, 3+4 or Gleason 4+3).Secondary objectives are to determine effectiveness of…
A. To gain more knowledge about the prevalence of TBI in male prisoners in the PPC and the relationship of TBI with violent crime and aggression. We expect that TBI is more common in violent offenders than in non-violent offenders. More specific, we…
To determine the within and between variability of pharmacokinetic (PK) profiles in patients treated with DOACs in daily practice
a. To investigate the phenotype and function of immunological cells present in endometrial and peripheral blood of women with a history of recurrent miscarriages and women without any known pregnancy complications.b. To investigate the association…
To assess the safety, tolerability, biomarker and cognitive efficacy of investigational products in subjects who are known to have an Alzheimer*s disease-causing mutation by determining if treatment with the study drug slows the rate of progression…
to identify novel molecular pathways resulting in premature atherosclerosis (PAS) in families where the traditional risk factors are not present / near absent.
The main objective is to identify the source of the *musician effect*, particularly for speech perception. The underlying processes involved and individual differences in different groups of participants in speech and music perception, both in quiet…
We hypothesize that verapamil reduces progression from paroxysmal to persistent AF, improves rate control, exercise tolerance and quality of life and reduces costs compared to metoprolol.
The purpose of the current study is to examine the additional diagnostic value of the stress radiograph in determining deltoid ligament disruption in ankle fractures. The sensitivity and specificity of this test will be compared with findings on MRI…
To investigate whether perturbation of the left middle temporal gyrus results in immediate adaptation in the right hemisphere, indexed by a shift of alpha-beta oscillatory effects from the left to the right hemisphere.