2535 results
To investigate whether increased aldosterone levels in obese individuals lead to impairment of microvascular function through reduction of NO-availability, and to establish the role of microvasculaire dysfunction in the pathogenesis of salt-…
Aim of the study is to compare the efficacy and safety of the use of a low vacuum constant drainage system (Palin®) with a high vacuum closed suction drainage system (Medinorm S-400®) after chest wall masculinization in female-to-male transgenders.
1. Primary objectiveThe identification and discrimination of AF burden and the patient burden of the nECG system in patients with paroxysmal AF undergoing catheter ablation for AF.2. Secondary objectiveAssess the relation between the changes in…
To study whether selected allogeneic bone marrow derived MSCs are safe by assessing the composite end point Biopsy Proven Acute Rejection (BPAR)/ graft loss at 12 months
Using a variety of methods, we try to determine the dynamics of the chewing movements in typically developing children and children with CP. The methods are, in some degree, complementary to each other. Given the limitations of the methods we need…
The primary objective is to determine if there is an association between the presence of vertebral and/or rib anomalies and congenital malformations, aneuploidy or adverse fetal outcome, in order to assess whether detailed evaluation of the…
Aim of this study is to see if the use of an anti-adhesive medical device, the FlexiSurge, is safe to use against adhesions that arise after open abdominal surgery.
Primary Objective: To define a top set of genes that most reliably (r >=0.95) distinguish psoriasis from normal skin. We will define this set from differential methylation genes to indicate potential biomarkers.Secondary Objective(s):…
The aim of this study is to identify risk factors for development of cardiovascular disease after TC treatment.
Determining the feasibility and diagnostic accuracy in terms of sensitivity and specificity of intraoperative detection of peritoneal carcinomatosis of colorectal origin by intraoperative fluorescence imaging using the VEGF-targeting optical imaging…
Primary objective of the study is to investigate whether Behavioral Activation for Negative Symptoms (BANS) improves negative symptoms. Secondary objective is to investigate whether effects of BANS on negative symptoms is mediated or moderated by…
To investigate if the active product shows a postprandial plasma triglyceride profile different from the control product in healthy adult male volunteers.
The focus of this pilot study is to investigate the results of a sialendoscopy (with or without rinsing with hydrocortisone 100mg) on the unstimulated whole mouth (UWS) and stimulated parotid (SP) (ml/min) flow of saliva, oral dryness, reported…
1. To investigate if PMN of patients with sickle cell disease are prone to form NET when compared to PMN of healthy controls.2. To investigate if red blood cells of sickle cell disease patients promote NET formation of PMN in sickle cell patients as…
In the present study we will determine the effect of sympathetic blockade by TEA on major outcome parameters after off-pump CABG.
The aim of this study is to investigate the host tissue response to the implanted collagen inlay in implant based breast reconstruction. Secondary, we want to investigate if the presence of capsular formation is associated with the presence of…
The primary objectives of the study are to evaluate the safety and performance of the Horizon* AAA Stent Graft System.
To investigate the effect of anti-IL6 therapy with tocilizumab on subclinical arterial inflammation (endothelial dysfunction) and stiffness in patients with treatment resistant rheumatoid arthritis at baseline and after 6 months treatment
The primary objective is to determine feasibility of DRUJ cartilage quantification on ultra high field strength 7T MRI by imaging healthy volunteers and OA patients. Feasibility means succesfull imaging DRUJ cartilage for all subjects. The two…
In the current research proposal, we aim to translate these preclinical findings to the human situation and test the hypothesis that MR antagonists limits IR-injury in human myocardial tissue. Secondly, we will test the hypothesis that the…