272 results
To discover human genes which are likely to confer susceptibility for recurrent respiratory papillomatosis
The primary objective of the PROTI study is to establish whether patients can correctly determine which treatment assignment they received during the randomised phase of the trial.The key secondary objective is to compare the rate of withdrawal from…
Primary Objectives:• show effectiveness of the SMSC instrument in 3D correction of the spine prior to placement of the implants.The hypothesis is that to achieve de-rotation of the spine without failure of the pedicle screws, de-rotation has to be…
PRIMAIRYThe primary objective of this trial is to evaluate the efficacy of atacicept compared to placeboin preventing new flares in subjects with SLE.SECONDARYSecondary objectives of the trial are:• To evaluate the safety and tolerability profile of…
The main objective is to compare the coronal Cobb angle correction of proximal hook claw fixation versus proximal pedicle screw fixation after two years of follow-up. The secondary objectives of the study are: comparison of coronal Cobb angle…
The primary objectives of this study are: • To determine the longterm safety and tolerability of rhHNS administered via an intrathecal (IT) route once monthly for 8 years in patients with MPS IIIA, who have received and tolerated 6 months of…
The goal of this study is to collect and clinically characterize a large cohort of patients with hereditary retinal dystrophies in the Netherlands. The study cohort will be used to identify the genetic causes underlying these diseases, and to…
- to determine possible differences in the results of the ABILHAND kids questionnaire between parent, occupational therapist and rehabilitation doctor- variance of the results in time
Primary objectives:1. To determine the effect of the use of a tailored intervention protocol (regarding reduced antimicrobial use, improving hygiene and changing the animal contact structure) on pig and veal farms on the degree of antimicrobial…
The goal of the present study is twofold. The first one is to develop a Recogntion Task for adolescents with OCD analogue to the Recognition Task for adults. This Revised Recognition Task can afterwards be used for measurement of the effectiveness…
1. To investigate the efficacy of Cogmed working memory training in reducing behavioral symptoms in children with neuropsychiatric disorders and borderline intellectual functioning.2. To investigate whether WM training improves neurocognitive…
Primary objective:- Collecting and setting up norm values for the Steep Ramp Test for healthy children and adolescents between 8 and 18 years (what is the maximal attained work rate (Wpeak) during the Steep Ramp Test in healthy children and…
Ascertain feasibility, study burden, between-subject and within-subject variability of automated RH-PAT measurements in paediatric renal transplant recipients. Comparison of adipokines and inflammatory profiles in renal transplant recipients and…
Study the very long-term efficacy (regarding reflux control) of antireflux surgery in children with severe GERD.
Idenification of new Hirschsprung's disease associated genes.
Main objective This research focuses on the outcomes of domestic violence at various levels in the family system, where we consider the severity of domestic violence as a determining factor. The relationships in the model are tested in families…
Evaluation study on the effectiveness of a new developed vaginal dilatation programme for medical-psychological treatment of vaginal hypoplasia / agenesis.
The objective of this study is to gain insight in HIV infected children in the AMC in:.- the prevalence and clinical signs of livertoxicity - an association between the different compounds of combination anti-retroviral therapy (cART) and…
To compare the oxygenation and oxidative metabolism in skeletal muscles of patients with CF with healthy controls to provide insight in the metabolism in patients with CF.
To study the outcome in boys with a history of UTI or with persistent incontinence who underwent cystoscopy and endoscopic treatment in case of obstruction, compared to boys who did not have cystoscopy.