846 results
The purpose of this study is to determine the need for thromboprofylaxis in patients being treated in a below-knee plaster cast after trauma of a lower extremity and if there is, to assess if both of the two tested prophylactic treatments are suited…
To investigate prospectively how the "TAMRO-profile" performs in a pre-operative treatment setting. In addition we can examine whether the profile is specific for tamoxifen or is predictive for endocrine resistance in general. Also the…
Study phase 1: In patients with BO undergoing work-up endoscopy for early neoplasia, we aim to develop a classification to evaluate fluorescence spectroscopy of neoplastic and non-neoplastic lesions in Barrett epithelium, as used in phase 2.Study…
Hypothetically, in patients with PBC or PSC the FGF-19 production or -response could be altered. The goal of this research is to study the FGF19 production after a standardized oral fat challenge and the effect of this FGF19 production on bile acid…
The primary objective is to study changes in synovial inflammation in serial biopsy samples following the administration of abatacept in patients with active rheumatoid arthritis.The secondary objectives of this study are to (I) assess clinical…
To investigate the validity the dynamometer the KinCom in comparison to the Biodex dynamometer.
To assess whether close rectal restorative proctocolectomy with IPAA has a better outcome regarding postoperative vaginal vasocongestion and reported psychological and sexual functioning then IPAA by TME restorative proctocolectomy.
Primary Objective:To determine breathprint variation of intubated and mechanically ventilated patients planned for elective surgery.Secondary Objective(s):Correlation between breathprints and (1) oxygenation, (2) biological markers of oxidative…
The purpose of the study is to determine whether PICSO is safe and feasible using a femoral approach, and in what amount of cases PICSO is effective to increase collateral flow index (CFI).
The aim of the study is to assess the relation of gingival abrasion to recession in both manual and power brush users.
To calculate the repeatability and reproducibility of MRE stiffness measurements in the liver on a voxel-by-voxel basis.
In this study, we will assess whether healthy and hypertensive subjects with high-normal serum CK display greater salt retention and vascular contractility, compared to those with low-normal serum CK.
To obtain more information on peripheral muscle properties that can account for the reduced exercise capacity in patients with PPS compared to healthy subjects, and to develop an alternative method for determining aerobic exercise capacity in…
The main objective of the study is to determine whether PCI for in-stent restenosis with a drug eluting balloon is angiographically non-inferior to PCI with a drug eluting stent at 6 month follow up.
Cholesterol absorption inhibition (%) calculated from plasma concentration vs. time curves from labeled cholesterol, for the PS or PSE containing products, compared to a control product without PS or PSE.
To gain more insight into the pathogenetic processes involved in SS by analyzing the infiltrate and structural changes in salivary glands of SS patients and compare these findings to those in other (aspecific) inflammatory and non-inflammatory…
to measure peripheral insulin sensitivity and intramyocellular concentrations of different FA metabolites (ceramide, gangliosides, diacylglycerol and triacylglycerol) known to interfere with the insulin signalling cascade during infusion of…
To study whether the lower cholesterol absorption rates of the Dahlia-2a study were due to lower bioavailability of the oral D7-cholesterol tracer.
Assess the efficacy and safety of eculizumab in pediatric patients with aHUS to control TMA as characterized by thrombocytopenia, hemolysis and renal impairment.
The aim of the study is to investigate whether there are differences in esophagogastric junction distensibility, acid entrapment in the hiatal sac and rate of TLESRs in the pre and post-surgery state.