295 results
The primary objective is to establish whether prefrontal compensatory mechanisms during working-memory performance may be enhanced by working-memory training, both in healthy older adults and MCI patients. The secondary objective is to establish age…
We hypothesize a lung*protective mechanical ventilation using lower tidal volumes during general anesthesia for minimally invasive transthoracic esophagectomy to protect against postoperative pulmonary complications in patients undergoing minimally…
We want to describe in detail the MTH-induced changes in pro- and anti-inflammatory markers in patients after CA. We further aim to evaluate the relation between neurological outcome and levels of pro- and anti-inflammatory markers.
To investigate the dynamic changes in bone marrow adiposity during the menstrual cycle as assessed by Dixon*s Quantitative Chemical Shift Imaging (QCSI) measurements and to determine the role of estrogen in these changes.
To monitor the systemic effects of radiotherapy (RT) alone or in combination with concurrent chemotherapy (CRT) (Cisplatin) on the immune response and T-cells over time in patients with HPV+ head and neck squamous cell carcinoma (HNSCC).
PrimaryTo determine whether the palatability of a newly developed formulation of valacyclovir is non-inferior to administration of crushed and suspended tablets in children, is the primary objective of the second phase of the trial.The primary…
To develop TMS-EEG as a technique to study the interaction between brain regions. The specific experiments in this study are aimed at investigating the effects of brief activations of specific brain regions using TMS on signals recorded non-…
Primary objective1) To study the frequency of mutations in this gene in patients with central hypothyroidism and their first- and second-degree relativesSecondary objective: 2) To determine the clinical, biochemical and radiological consequences of…
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To assess the clinical and cost effectiveness of the anterior approach, compared to the conventional posterolateral approach for THA in terms of physical functioning and health-related quality of life
The primary study objective is to evaluate the psychophysiological effects of a psychological expectancy training directed at optimizing immune function compared to a control group in healthy male subjects.
We aim to extend our recent work on fundamental mechanisms that underlie automatic influences of reward on attention to clinical populations that suffer from reduced and excessive reward-driven behaviours. That is, we will investigate whether…
Objective of this study is to determine if Optical Coherence Tomography (OCT) measurements are a reliable measure of the severity of neurological impairment in patients with X-ALD and ZSD and therefore if OCT is an acceptable "surrogate"…
To describe the wound related complication rate in post-bariatric body contouring surgery patients who are treated according to a new guideline and assess the factors associated with a higher complication rate.
We aim to conduct a five year follow-up amongst the X-ALD carriers and assess their current symptomatic and biochemical status. This data will provide new insights in the progression of the disease in carriers. Moreover we would like to validate a…
- To assess whether the implementation of a deep neuromuscular block (NMB) (PTC 1-2) combined creates optimal surgical conditions as measured by the surgeon (using the 5-point Leiden surgical rating scale) versus a moderate neuromuscular block (TOF…
The main objective of this study is to investigate the effect of a topically applied emollient enriched with barrier lipids on the barrier properties of skin of AE patients.
To study the effectiveness of protein-enriched meals and bread in increasing daily protein intake with at least 14.5g among in-home assisted community-dwelling older adults, in order to reach the daily protein recommendation of 1.2g per kg…
The aim of the study is to test whether EMDR is effective to use as an intervention in order to reduce the severity and the burden of tinnitus and to determine whether the alleged effect of treatment is stable.
The study comprises 2 parts.Part 1: Primary: to assess sexual functioning, sexual self image and psychological and relational functioning in MRKH women with surgical or non- surgical created neovaginas and their partners and make a comparison with…