18 results
The overall aim of the project is to define effects of genetic and non-genetic variants on pharmacological treatment response in children with asthma. The following questions will be answered:- What are the characteristics of children who do not…
1. Description of the epidemology of dystrophinopathies in the Netherlands2. Description of the natural course of dystrophinopathies in the Netherlands and the influence of medical development on it.3. The initiation of a database for patients…
We propose to investigate the health related quality of life (HRQoL) in childhood survivors of refractory GvHD who have been treated with mesenchymal stem cell transfusions. This will be a multi center study involving the Division of Clinical…
The main objective of this study is to investigate whether under-recruitment of the prefrontal cortex and poorer performance during manipulation of working memory in children is a result of immature neural circuitry or of limited practice.
The primary purpose is validation of the dutch version of a brief health-related quality of life (HRQOL) tool in children with systemic lupus erythematosus (SLE). This tool is called *Simple Measure of Impact of Lupus Erythematosus in Youngsters© (…
Systematic gathering of biomaterial and phenotypic data of IBD patients during clinical care provides assessment of molecular markers in the DNA, the transcriptome and proteome. The markers can be associated with the different disease phenotypes…
Not relevant
The objectives of this study are:1) assess the differences in pain sensitivity between children with and without chronic pain2) collecting normative data for pain sensitivity in children aged 8-123) investigate the relationship between parental…
The objective of this study is to find out whether there is a relationship between attachment (problems), emotional problems and chronic pain in adolescents. It is aimed to improve the knowledge on the causes and maintaining factors of chronic pain…
This study aims at evaluating what children attending burn camp and their parents appreciate about the Dutch pediatric burn camps and aims at identifying its possible effects on self-esteem, body image and dealing with burn-specific social situation…
The assessment of the duration of the cellular immunity to Bordetella pertussis after an extra ACV booster and the relationship between the memory B- cells and antibody responses. The methods used in the study are:B- and T- cell memory responses and…
Primary: To provide insight in the prevalence of diagnosed cases of IgG-subclass and/or antipolysaccharide antibodydeficiency in Dutch children. Secondary: To provide insight in the diagnostic process, the clinical presentation, the therapies used…
Heart rate variability in obese adolescents in relation to insulin levels during OGTT.
A pilot study
The aim of the project is to study the relation between hyperinsulinemia and changes in autonomic tone in adolescents with obesity. We have chosen to perform a pilot study, because of lack of comparable studies in the literature.
The objective of this study is to determine whether the dichotomization in good and poor outcome by the composite scale, corresponds better with the parents' and doctor's opinion on the outcome than the PSOM. The composite scale willl be…
Primary goal:Determination of the number of MRSA-carriers among persons in the direct surroundings of a person (index) with an infection by MRSA.Secundary goal:1. To determine if and how MRSA-colonisation spontaneously (dis)appears or spreads among…
The aim of the proposed study is to conduct an evaluation of the validity of web-based completion of the (Child-) ACT on the basis of comparison with paper-based completion and to test reproducibility of both web-based and paper-based version.…
The main objective of this multicentre interdisciplinary study is to systematically aggregate data on moderate and severe traumatic brain injury patients in a national database. This database will serve to:a. get an estimation of the incidence of…
Identifying subsets of Crohn's disease (CD) at risk for poor outcomes is a priority in pediatric CD research. Having the ability to predict patients more likely to relapse, to be refractory to therapy or to develop complications may enable…