140 results
The aim of this study is to determine whether multiparametric MRI (mpMRI) of the bladder, in combination with an outpatient biopsy for histological confirmation, is a faster, safer, cheaper and therefore more cost-effective way to detect or…
To study the impact of addition of the GAAD score to imaging in patients with chronic liver disease eligible for HCC surveillance.
To investigate the feasibility of Bergström needle biopsies of the vastus lateralis muscle, and NIRS measurements of the gastrocnemius muscle in post-ICU patients.
The primary objective of this clinical feasibility study is to assess the overall diagnostic yield of the Investigational Device in comparison to standard care. The secondary objective is to assess the safety issues that possibly occur while using…
IVD1: The primary objective of this clinical performance study is to evaluate the effectiveness of the MyChoice® test in identifying HRRm or non-HRRm mCSPC patients as part of the enrolment criteria for EvoPAR-prostate01. This clinical performance…
In the current study, we aim to assess the energy requirements of professional football players during different phases in the rehabilitation from an ACL reconstruction. As such, this study will identify the energy and nutritional requirements,…
This proposal aims to evaluate the use of STE as a diagnostic tool for early diagnosis of impaired fetal growth in twins. The results from this proposal will be beneficial from a public health perspective, as it will lead to accurate and early…
Hand function impairment in systemic sclerosis: Outcomes, Mechanisms and Experience (HANDSOME) study
Primary Objective: Determination of risk factors for hand function impairment in systemic sclerosis (SSc) patients with early disease, very early disease and established hand impairment (contractures) at 2 years follow-upSecondary Objective(s):-…
The primary objective of the CRT-DRIVE study is to test the hypothesis that at least 75% of patients undergoing a CRT implantation guided by non-invasive electrical and venous anatomy assessment (XSPLINE technology) will show a reduction of left…
The primary objective is to investigate the feasibility of NIR fluorescence imaging with intra-arterial ICG to detect differences in foot perfusion following successful endovascular lower extremity revascularization.
IRDs are genetically diverse (280 causative genes have been identified to date) (https://sph.uth.edu/retnet/) and have vastly different clinical manifestations, including age of onset, severity of disease, rate of progression, and structural and…
Objective: We aim to 1) monitor and investigate the change in serum metal ion (Cobalt and Chrome) levels postoperatively (at 3-6, 12 and 24 months) in patients receiving a primary PEEK HD coupling mechanism, monitor and investigate the change in…
In the Netherlands, TEE is currently not used in emergency departments during cardiac arrest. The purpose of this study is to investigate if point-of-care TEE can be used effectively and safely in patients with cardiac arrest.
Identifying placental disease during pregnancy using cfDNA of placental cells in the maternal circulation to discover new therapeutic placental targets for fetal treatment.
To establish the performance of the idi-CGM system among persons with DM.
The study aims to determine the feasibility and diagnostic accuracy of quantitative Magnetic Resonance Imaging (MRI) techniques for determining the presence of portal hypertension in patients with severe liver disease. The secondary objectives are…
Our central hypothesis is that the RNA content of TEPs allows for the identification of glioblastoma progression, including the differentiation from pseudo-progression and radionecrosis. For this we plan to use two parallel approaches, i.e. the TEP-…
The primary objective of this study is to demonstrate that the EnzySystem HemA version A can record TG and quantify FVIII activity levels within a time frame of 60 min in fresh whole blood samples of healthy volunteers and patients with hemophilia A…
We aim to determine the added value of a direct FET-PET for clinical practice. The hypothesis is that the addition of FET-PET will lead to correct diagnosis more rapidly than regular MRI alone, and thus to a better quality of life for patients…