436 results
Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.
The rationale of this study was to investigate the alteration of colonic motor patterns in the early postoperative stage and between patients with no or minor LARS-symptoms (LARS-score < 30) compared to patients experiencing major LARS…
The standard-of-care sentinel lymph node (SLN) procedure in paediatric cancer patients consists of a preoperative intradermal injection with 99mTechnetium-nanocolloid as radiotracer in combination with an intraoperative injection of blue dye for…
The primary objective is to investigate the differences in mentalizing abilities between outpatients with chronic pain and a control group, consisting of outpatients with painful acute injuries or painful somatically explained conditions. The…
The main objective of this study is to identify cortical brain regions that show significant altered fNIRS activity during FOG in patients with PD. This is accomplished by considering four secondary objectives. First, we compare the cortical…
To determine the accuracy of US for detecting disease activity in paediatric patients with IBD and to develop an easy-to-use and accurate US-activity index that can accelerate and improve clinical management by reducing the need for gastrointestinal…
Primary Objective: To evaluate persisting pulmonary morbidity and echocardiographic signs of pulmonary hypertension in young adults born with CDH that interfere with physical fitness and participation in society.Secondary Objective(s): To evaluate…
This study has been transitioned to CTIS with ID 2024-512030-15-00 check the CTIS register for the current data. Our primary objective is to assess the effect of diltiazem on coronary microvascular function as assessed by coronary reactivity testing…
Primary Objective:Our primary objective is to investigate the changes in CSR of the lower trunk muscles in subjects with an episode of recurrent LBP and compare them with healthy subjects.Secondary Objective(s):Our secondary objective is to explore…
The main purpose of this pilot study is to investigate the feasibility of fluorescence imaging using cetuximab-IRDye800CW for intraoperative margin assessment in patients with cutaneous squamous cell carcinoma.
What has so far been underexplored in the study of molecular signatures in atopic dermatitis is a wide systems biology approach, in which multiple analysis techniques (a so-called multi-omics approach) are applied in a clinical setting where…
With this project, we aim to validate Cytocam-IDF imaging as a routine monitoring tool in critically ill patients. To this end, we will compare Cytocam-IDF imaging to an invasive hemodynamic monitorization tool (PiCCO) in terms of comparability and…
We aim to determine if in vivo MSOT can distinguish benign from malignant thyroid nodules by correlating and validating optoacoustic signals in vivo with pathology results.
This study consists of two subsequent phases, with different objectives. The first phase includes a technical, explorative part with the objective of determining appropriate cut-off values and incubation times for the Sofia 2 Lyme+ WB FIA compared…
Primary objective:* To investigate the consequences of (recurrent) hypoglycaemia on inflammatory responsesSecondary objectives:* To study the atherogenic consequences of (recurrent) hypoglycaemia* To study the molecular mechanisms involved in the…
Primary objective: To determine the prevalence of AKI in critically ill children based on clearance of iohexol.Secondary objectives:1. To determine the prevalence of AKI in critically ill children using serum creatinine, creatinine clearance,…
Primary objective: To test in patients with ESRD whether a longer HD session (8 hours) compared with CHD limits the decline in cerebral blood flow.Secondary objectives: 1) to investigate whether a longer dialysis session is associated with superior…
To evaluate the long-term neurodevelopmental outcome in two groups of children with FNAIT. First, children with unanticipated disease *index cases* that were born without maternal IVIg administration during pregnancy. Second, children with…
Primary objective: To investigate the prevalence of bruxism and TMD in PD patients through objective measurements and to identify factors associated with a higher risk of developing these symptoms.Secondary objectives: - To investigate the salivary…
The aim of the study is to document changes in CTO vessels physiology post PCI and at 3 months follow up. We intend to look for correlations between anatomical features identified with intravascular imaging and physiological parameters, how these…