27 results
Development of new imaging techniques for MR-guided motion management in the presence of respiratory motion
Objective: This protocol describes a framework that will be used to create different studies. The general primary and secondary objectives of this protocol are stated below:Primary objective: Investigate the effect of surgery on the position and…
To evaluate whether we can determine the health status of the joint by measuring biomarker levels using a newly developed assay by the University of Twente based on the multiplex measurement of a panel of relevant biomarkers using Surface Plasmon…
The first aim of this study is to use an in vitro approach using patient's derived material to accurately and rapidly predict the optimal therapeutic approach that will predict a good clinical response in individual patients…
The primary objective of this study is to evaluate the feasibility and diagnostic accuracy of pre-operative MRI scanning using SPIO compared to lymphoscintigraphy (LS) and single-photon emission computed tomography/computed tomography (SPECT/CT)…
The primary objective is to examine relationships between neurocognitive performance and MRI parameters of brain vasculature, metabolism, and white matter diffusion in children who have been treated for posterior fossa tumor. Secondary objectives…
To develop a prediction model for BPD using a range of multimodal predictors assessed in the first two weeks of life.
We will combine four 7 Tesla MRI markers in extremely preterm infants (MRSI; SWI; PC-MRI; ihMT) to assess (1) if they can predict outcome until 2 years of age; (2) if they are of added value to 3 Tesla prematurity (Kidokoro et al., 2013) and (3) if…
The primary objective of this clinical performance study is to evaluate the effectiveness of the B7-H4 (A57.1) Assay in identifying B7-H4 positive (B7-H4 membrane staining at any intensity in ≥25% tumor cells) ovarian, endometrial, biliary tract,…
The aim of this study is to determine whether multiparametric MRI (mpMRI) of the bladder, in combination with an outpatient biopsy for histological confirmation, is a faster, safer, cheaper and therefore more cost-effective way to detect or…
The primary objective is to assess diagnostic accuracy of MRDTI/BTI for first and recurrent CVT in patients referred for MRI/MRV in the setting of routine clinical setting. The secondary objectives are to optimize MRDTI/BTI sequences for imaging…
The objective of this study is to support the pharma partner*s Phase III trial using Tina-quant Lipoprotein (a) RxDx assay for subject selection and optional batch testing of follow-up samples. This study is carried out to evaluate the performance…
Determination of the (cost)effectiveness of the replacement of the expensive, risky and time-consuming food challenge test bythe Basophil Activation Test (BAT) for the diagnosis of an IgE-mediated cow*s milk allergy in children.
Primary objective: Determine correlation between RFS parameters (5 independent signal characteristics) and non-invasive hemodynamic parameters (estimated left ventricular end diastolic pressure, left ventricular ejection fraction, left ventricular…
The objective of this study is to establish the clinical performance of VENTANA PD-L1 (SP263) CDx Assay as a companion diagnostic (CDx) for the identification of patients with NSCLC who may benefit from treatment with [redacted]. …
The objective of this study is to determine the ability of respiratory EMG measurements with a wearable to …
The objective is to improve the understanding of intracochlear electrocochleography for objective measurement of residual hearing. ECochG responses obtained postoperatively in patients with different aetiologies will be evaluated in…
The main objective of the SOPI study is to select the HRD test that best predicts longest PFS on PARP-i in non-BRCA1/2 EOC patients, in order to adequately select patients that will benefit from a PARP-i. Secondary objectives are: to…
Primary objective Primary objective is to create a prediction model based on early clinical screening of motor, cognitive, and emotional disturbances to predict restrictions in participation at one year after cardiac arrest in patients that have…
The aim of this study is to validate the ultrasonographic hepatorenal index in children with overweight, obesity and morbid obesity, by using MRS.