5016 results
The primary objective of this study is to evaluate the added value of PSMA PET/CT and PSMA-targeted biopsies of PSMA-avid lesions in detecting ISUP GG ≥ 2 prostate cancer in patients with a negative or equivocal MRI (PIRADS 1-3) and a PSA density…
To assess the diagnostic accuracy of EIN in OES, with emphasis on underdiagnosing invasive tumors. Examen whether the five diagnostic criteria for EIN (architectural gland crowding, altered cytology, a minimum size of 1 mm, exclusion of carcinoma,…
The purpose of this study is to determine whether a NightWatch worn on the leg detects the same seizures as a NightWatch worn on the arm. In addition, the signal quality of both devices will be examined.
The primary objective of this study is to evaluate the clinical performance of the VENTANA PD-L1 (SP263) CDx Assay in terms of its ability to identify patients with non-squamous stage IV or recurrent NSCLC who may benefit from treatment with…
The main objective of this study is to validate the specificity of 100% for peripheral thrombocytopenia of an IPF cut-off value of 13% in our patient population and workflow. In addition, if the specificity of 100% cannot be validated at a cut-off…
To study the prevalence of distinct congestion phenotypes and study their association with response to therapy and outcomes
Primary objective: To evaluate the variability of ABV measurements using an amended measurement protocol with the aim of achieving a variability of <= 10%.Secondary objective: To evaluate the effect of reducing bolus volume on variability
Primary Objective 1.Study the feasibility of a physiological stressor (breath-holding maneuver) and its effect on myocardial perfusion [13N]NH3 Total-body PET/CT with stress adenosine as a reference, in healthy volunteers and in CAD patients. Breath…
Assessment of reference values in plasma of renin and aldosterone and in 24h urinary of aldosterone (Aldo-18G and TH-Aldo) before and after a 3-day oral salt loading test , respectively. In addition, establishing assay specific conversion factors…
To support the AstraZeneca ARTEMIDE-Gastric01 clinical trial by testing for PD-L1 and HER2 expression in FFPE tumor specimens for eligibility and stratification.The primary objective of this clinical performance study is to evaluate the…
The primary objective of the study is to explain poor speech understanding at an individual level, with the ultimate goal of finding optimal personalized settings for the speech processor. We use the new measurement method of direct stimulation…
The main objective of this study is to develop a diagnostic model with high sensitivity and specificity to help pediatricians to recognize malignancy and minimalize unnecessary referral in children with lymphadenopathy. Moreover, we will perform a…
1. The main objective of the first study is to construct a questionnaire for pediatric patients, that can differentiate between ACNES and non-ACNES patients in an functional abdominal pain/abdominal pain of unknown cause population. Parameters:- A…
To increase subject comfort during scanning, and to test, evaluate and improve new methods that enable acoustic noise reduction in MRI.
For Lilly's study (drug study)Primary Objectives:Dose Optimization- To determine the optimal dose of LY3537982 (50 or 100 mg BID) to be administered in combination with pembrolizumabSafety Lead-In- To determine the dose of LY3537982 to be…
Reliability of prehospital triage with HEART-score in patients with thoracic complaints/pain appropriate to a suspicious ACS