123 results
The primary objective is to determine the safety and tolerability BCG vaccination followed by controlled human malaria infection; and to determine the protective efficacy BCG vaccination against a controlled human malaria infection.
Primary Objective: To determine the safety and tolerability of NF135.C10 sporozoite immunization under chemoprophylaxisSecondary Objectives:• To determine the dose-dependent protective efficacy of NF135.C10 CPS-immunization against homologous…
The main aim of the EuroFIT trial is to assess the effectiveness and cost-effectiveness of the EuroFIT programme in supporting men to achieve an increase of at least 1000 steps per day (about 10 minutes on average per day, or 70 minutes per week)…
1) To evaluate the efficacy of knee-ankle-foot orthoses (worn by night) in preventing a decrease of range of motion to ankle dorsiflexion in children with cerebral palsy (Clinical part). 2) To evaluate the effect of night-worn knee-ankle-foot…
To evaluate the influence of dynamic light on the disturbance of the rest-activity rhythm of patients admitted to the haematology ward of the Erasmus MC- Daniel den Hoed Cancer Centre.The results of the study can possibly be used in the future…
The primary objective is to evaluate the safety and efficacy of anakinra in patients with multiple myeloma receiving high-dose melphalan (HDM) in the preparation for an autologous hematopoietic stem cell transplantation (SCT). Secondary objectives…
The objective of this research is to develop a method which can identify among all consanguineous couples the ones which are at high risk.
To assess whether supplemention of vitamin D3 (1200 IU/day) in vitamin-D deficient non-western immigrants at risk for type 2 diabetes mellitus can improve the insulin resistance and betacell function as well.
To assess the preemptive effect of Bepanthen® on decreasing the incidence of specific >= grade 2 dermatological side effects of interest in respect of compliance to EGFRI agents, HRQoL and the adherence during the 6-week skin treatment period…
The aim of this study is to assess the efficacy of Cryolijm SQ (Sanquin blood supply foundation, Groningen, The Netherlands) fibrin sealant in reducing postoperative drainage at the abdominal donor site which could result in earlier drain removal,…
Measurement of the pain index, NoL, during laryngoscopy, intubation and skin incission during variations in de level of propofol and remifentanil.
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In the proposed study, two main issues will be addressed: first, it will be studied whether a high dose (4.0 mg) of FA supplementation periconceptional has an added value over the now recommended low dose of 0.4 mg in the prevention of congenital…
An information campaign was developed targeting early-stage KHOA patients and healthcare professionals (HCPs) to optimise timing of referral to secondary care.
This study aims to further reduce the incidence of a post-ERCP pancreatitis by administrating a single gift antibiotics after the procedure.
The goal of the study is to develop a state-of-the art- lifestyle intervention that is achievable and acceptable for patients with a bipolar and severe recurrent depressive disorder. and patients in general practice with depression
This prospective evaluation of the dynamics of thyroid hormones during cancer treatment in children is designed to determine the prevalence of thyroid hormone deficits at diagnosis, during and directly after treatment and to study changes in thyroid…
The aim of the study is to document the presence and/or post-operative development of PVD and to assess its influence on the incidence of PRD in myopic patients in a time period of three and five years after lens surgery.
To investigate in our defined HF patient population if monitoring in combination with motivation on physical activity leads to an increase in enrollment rate for cardiac rehabilitation and sustained physical activity after cardiac rehabilitation as…
To determine the impact of BCG vaccination on the incidence of clinically relevant respiratory infections or COVID-19 in vulnerablel older adults.