144 results
The primary study endpoint is the respiratory exchange ratio (RER) during the night. The secondary objectives are to examine how differentially timed exercise affects 1) 24h energy and substrate metabolism and 2) the immune response based on…
To investigate the impact of the daily consumption of a mealworm- and whey protein supplement on muscle damage upon physical exercise in vital active elderly.
The primary objective of this study is to establish the relationships between structural and neural adaptation of human skeletal muscle when muscles are exposed to overstretch and overload through exercise.
The aim of this exploratory study is to compare the effect of a lifestyle intervention program consisting of combined individual coaching and group sessions (CLI) with a lifestyle intervention program with individual coaching only (II).The program…
To investigate the effect of adding PIFM strengthening exercises to a functional exercise program compared to a functional exercise program alone on maximum gait speed in mobile older adults. The secondary objective is to also investigate the effect…
Primary objective - to describe immunogenicity and safety in healthy volunteers of the intradermal dermal delivery of a single fractional dose of 20µg mRNA-1273 LNP vaccine (Spikevax, Moderna) more than 3 months after primary vaccination with…
Immunogenicity:To determine the immune response in terms of GMT fold-rise for neutralising antibodies against SARS-CoV-2 following a single booster dose with VLA2001Safety:To assess tolerability of a VLA2001 booster vaccination
This study has been transitioned to CTIS with ID 2024-510729-24-00 check the CTIS register for the current data. Primary Objective• To evaluate the efficacy of eptinezumab as add-on to BI for the prevention of migraine and treatment of MOHSecondary…
Primary: to investigate the effectiveness of using Hospital Fit as part of the physiotherapy treatment on average time spent walking per day in patients hospitalised at the Medical Oncology or Cardiology Departments of the Maastricht University…
To investigate the short-term effect of a vegan diet on daily muscle fractional synthesis rates in comparison to an omnivorous diet in community-dwelling older adults.
The primary objective of this randomized controlled trial is to investigate the effect of the VR-TRAC on aggression in a prison-based population.
To assess the feasibility of a tailored eHealth intervention (primary) for cardiac patients with a low socio-economic position and explore its effect on patient activation, certainty and guidance (secondary) compared to usual care.
This study has been transitioned to CTIS with ID 2023-505836-36-00 check the CTIS register for the current data. Main Objective:To demonstrate the superiority of galcanezumab versus placebo in the prevention of migraine in (at least) 1 of the…
The general aim is to identify the relevance and feasibility of a cost-effectiveness study on exercise therapy in patients with early stage knee OA1. What is the feasibility, in terms of percentage of eligible patients recruited, for GPs to recruit…
The DAPARHT trial is designed to assess effect of the SGLT2 inhibitor dapagliflozin to prevent deteriorating renal function in heart transplant recipients. Secondary objectives are to assess the impact of treatment on: i) weight, ii) glucose…
There are large interindividual differences in tolerance for night work. The main factors determining this tolerance are largely unknown, and better identifying them - which is the aim of this study - may target preventive and mitigating strategies…
The aim of this study is to investigate the effect of low-dose Lithium on stem cell dynamics, the number and size of polyps and, to assess safety outcomes of this drug in FAP patients.
Evaluate the formation of adhesions after third-generation endometrial ablation, with and without the intrauterine adhesion barrier
To examine whether the Positive Psychology group intervention *Goed leven met een hartaandoening* [Living well with heart disorder] is effective in increasing mental well-being, ability to adapt, positive skills (e.g. savouring, positive re-…
Primary objective: - To establish a controlled human infection model in which healthy Dutch adult volunteers are inoculated with a wild-type Streptococcus pneumoniae bacterium with strict safety reviews.Secondary objectives: - To assess the…