36 results
The purpose of this study is to determine the need for thromboprofylaxis in patients being treated in a below-knee plaster cast after trauma of a lower extremity and if there is, to assess if both of the two tested prophylactic treatments are suited…
The HOPE-3 trial will evaluate the effects of lipid modification with rosuvastatin and of blood pressure lowering with candesartan/hydrochlorothiazide (HCT) and their combination in a wide range of middle aged people, who are at average risk for…
To assess in a cohort of patients with established FAP:1 The efficacy of MPA in terms of reduction of number of colonic polyps, by means of Endoscopic Appearance of Polyposis (EAP) index.2 The effect on histological parameters and biological…
The primary objective is to investigate whether insulin sensitivity can be preserved postoperatively, by giving a simple carbohydrate-rich drink before surgery. Furthermore, to investigate whether gastric passage will be enhanced postoperatively…
The present study aims at testing whether a CPC-mouthrinse has a potential to inhibit *de novo* plaque formation as compared to a placebo and hexetidine.
This project aims to finalize the development (Study A) and to evaluate the efficacy (Study B) of a personal, individually tailored PMPP with interventions directed to stop smoking by 30% and/or alcohol consumption by 20% for women who are planning…
The aim of this clinical study is to investigate whether the non-anaesthetic noble gas helium induces preconditioning (PreC) and postconditioning (PostC) in patients undergoing coronary artery bypass graft (CABG) surgery
The aim of this research is to study the effectiveness of a new preventive training (Living to the full) for adults with mild symptoms of depression, anxiety or fatigue.
The pattern of BMD behind the press fit isoelastic acetabular component during the two years after implantation.
The primary goal is to examine the influence of weather condition on thermal load of an endurance run. Secondary we want to investigate the influence of fluid- and nutritional intake and clothing on thermal load of an endurance run.
•To determine the effect of short-term Topiramate treatment on glucose metabolism including endogenous glucose production, whole body glucose disposal and glucose oxidation in obese women. •To determine the effect of short-term Topiramate on lipid…
The aim of this project is to investigate whether a first trimester model of 3D placental volume, 3D power Doppler measurement of the placental vascularization and/ or serum levels of PAPP-A, PlGF, PP-13, PAI, Ang-2, sFlt and SEng can predict early…
in this study we want to examine whether an Internet-based self-help intervention with a coach is more effective than the same intervention without a coach in terms of clinical outcomes, drop-out and economic costs. Moreover, we want to examine…
1) To examine the effect of a 12-week multidisciplinary treatment on endothelial function, intima-media thickness and blood cholesterol in obese children (8-17 years).2) Investigate the changes in vascular function in obese children (8-17 years).
To examine the predictive value of daily physical activity (steps/day) (DPA) of lung cancer surgical patients, measured by a pedometer, on postoperative morbidity.To examine the relationship between the daily physical activity (pedometer-assessed…
Which is the best way for cardiovascular prevention according to the Dutch general practitioner's guidelines, in a general pratitioner's office?a. By a nurse practioner, supervised by the general practitioner, while the frequency and…
The primary objective of the current study will be to evaluate the (cost)effectiveness of a PE intervention in order to prevent back and neck pain among a heterogeneous group of workers.
To improve physical activity levels and physical activity patterns in children with JIA by means of cognitive behavioural training based on the social cognitive theory and the health promotion model, delivered by internet and supported by group…
Are overweight or obese patients protected against atherosclerosis when suffering from haemophilia A? Is this association influenced by the severity of haemophilia? When the coagulation activity increases due to obesity (and inflammation), will this…
Striatal D2 receptor availability will be ascertained in 30 recent abstinent cocaine addicts by [123I]IBZM SPECT. In addition, we will measure drug craving and impulsivity with questionnaires, fMRI/EEG using cue-reactivity and impulsivity paradigms…