13 results
Primary Objective: 1. To compare total testosterone levels between male CCH and ECH patients and healthy controls To compare total testosterone levels in males with ECH during remission (remission ECH) and during an active…
The primary objective is to investigate if the stress-induced dynamics across stress systems are impaired in patients with CT-related depression compared to non-CT-related depression and healthy controls. The secondary objective is to examine how…
The aim of the study is:1) To test the effectiveness and cost-effectiveness of KIT for adolescents with (s)PTSD and comorbid symptoms. 2) To compare the outcomes from the current study with outcomes we have collected in two previous randomized…
To determine the effect of a five-week vegetarian diet on innate immunity of patients with a recent myocardial infarction and healthy participants.
In this study, we therefore aim to investigate how trained immunity is systemically regulated in kidney transplant patients and how the degree of trained immunity affects graft survival in patients. A better understanding of these processes…
To demonstrate the ability of using non-invasive 31P-MRS to monitor changes of in vivo markers of mitochondrial function in skeletal and cardiac muscles (i.e., skeletal muscle PCr recovery rate constant and cardiac PCr/ATP ratio)…
The aim of the THRIVE study is to examine two objectives: 1. What are the mechanisms through which friendships aid resilience?a. Does friendship support relate to reduced neural stress responses in young adults with CA?b. Does friendship…
To investigate the effects of a 5-day diet with 30% caloric and 70% protein restriction on cardiotoxicity induced by anthracycline treatment in women with triple negative or hormone receptor-positive breast cancer. The biomarker high-sensitivity…
To gain insight in the disease mechanisms of IBD, the immune system, gut and oral microbiome, environmental factors, the intestinal mucus barrier, intestinal epithelium, nutritional factors and metabolome will be studied in unaffected siblings of…
Primary objective: to register and investigate Dutch patients suspect for an inherited platelet function disorder, to assess clinical presentation, bleeding score, treatment, burden of disease and quality of life. Secondary objectives: to…
The main descriptive and analytic objectives are: Descriptive: To gather epidemiological evidence (prevalence, incidence) about the course of the mental, musculoskeletal and neurocognitive health (dependent variables) of…
To evaluate RRS with delayed RRO as an alternative for RRSO in BRCA1/2 gene germline mutation carriers. We hypothesize that RRS with delayed RRO leads to an equal ovarian cancer incidence when compared to RRSO.
To assess the impact of short-term forearm immobilization on forearm muscle glucose uptake and amino acid net balance and kinetics of individuals with T2D compared with a control group with normoglycaemia.