3830 results
To identify the patient profile for Actifuse and for other grafting products used to achieve bone fusion.
Primary objective:- To evaluate the effects of a 10 day-course of prednisolon on coagulation and fibrinolysis parameters in patients with mild-moderate astma, patients with severe asthma, and healthy controls.Secondary objectives:- To compare the…
To determinate the efficacy and safety of golimumab in rheumatoid arthritis patients in daily clinical practice during 48 months. In addition, the effect of treatment with golimumab on the lipid profile will be monitored during this study.
The objective is to investigate the effects of a combined strength and aerobic exercise program on cognition, physical functioning, social functioning and ADL.
To determine the long term clinical and immunological responses in patients with high grade VIN who have been vaccinated with an HPV 16 E6/E7 SLP vaccine approximately 3 years ago.
To objectify the effect of the VLS-system during daily use regarding postural stability and quality of life.
Primary objectivesPart A of the study (if applicable):1. To assess the safety and tolerability of tosedostat added to standard induction chemotherapy for AMLand select the feasible dose level for part B of the study2. To assess in a randomized…
To investigate the hypothesis that women with uterine prolapse stage 2 or more treated by laparoscopic sacrohysteropexy will have equal or lower recurrence rate of prolapse compared to women treated by vaginal sacrospinous hysteropexy.
To asses the effectiveness of surgery 7 and 10 years after conventional vaginal POP surgery compared with tension free vaginal mesh.
The proposed study will evaluate the efficacy of an internet-based cognitive behavioral intervention program designed to alleviate sexuality and intimacy problemens of women who have been treated for breast cancer.
To assess the potential benefit of pelvic floor therapy for anal fissure. Measured primarily in pain, measured by the VAS score. Secondary outcomes are healing rates and recurrence.
There is no high-level clinical evidence, with regard to clinical outcome, for the superiority of ESWT versus treatment with needling. The objective of this trial is to compare high-energy ESWT and ultrasound guided double percutaneous needling in…
Primary Efficacy Objectives• To compare the overall survival (OS) in subjects with malignant pleural mesothelioma receiving VS-6063 or placebo.• To compare the progression free survival (PFS) in subjects with malignant pleural mesothelioma receiving…
With this prospective registry we aim to evaluate the outcome of patients with a T2-T3 primary melanoma and minimal SN tumor burden, treated by CLND or nodal observation:* The main objective is to determine if T2-T3 melanoma patients with minimal SN…
Objective: the use of autologous platelet rich plasma (PRP) as an adjunct to the staged mucosal advancement flap to achieve a better closure rate of high peri-anal fistula*s.
The aim of this study is to identify the degree and direction of fluctuation from one to another renal function group within 2 months after discharge from hospital. In addition, prevalence of adaptations of the prescribed drugs that should result…
Our long-range goal is to develop a comprehensive, clinically and cost effective treatment for BPD that produces both symptom remission and functional recovery. We aim to determine the role that group ST can have in the comprehensive treatment of…
To determine the mechanism of action of propranolol in the prophylactic treatment of migraine.
Primary ObjectiveEstimate the proportion of subjects fulfilling criteria for symptomatic remission (as defined by Andreasen et al.)* following a transition to 12 months* treatment with flexible-dose PP3M in subjects with schizophrenia previously…
To compare the tidal volume distribution and other ventilator parameters between PAV+ and NAVA.