6 results
To find a simple test to explain non-responsiveness to sumatriptan in a proportion of patients with migraine.
To perform a percutaneous renal sympathetic denervation in a cohort of 20 patients with therapy resistant CPVT and LQTS patients and to objectify and evaluate the benefit of this novel treatment for this group of patients.
Aim of the study is to study a new therapeutic option for the treatment of hypertension
Primary Objective:- Number of participants with dose limiting toxicity - Number of participants with treatment-related adverse events - Number of participants with treatment-emergent adverse events- Number of participants with changes in vital signs…
Primary (Parts 1 and 2)• To evaluate safety and efficacy (per Response Evaluation Criteria in Solid Tumors version 1.1 [RECIST 1.1] by investigator) of 2 dose levels of tarlatamab Primary (Part 3)Evaluate safety of reduced mandatory monitoring…
Monotherapy (Parts A, B*, D, E, F and G)Primary Objectives - Evaluate the safety and tolerability of Tarlatamab - Part A only: Determine the MTD or RP2D of Tarlatamab Secondary Objectives• Evaluate preliminary anti-tumor activity of Tarlatamab •…