5 results
The objectives of the study are:To determine the pharmacokinetic profile of Xen2174 in plasma and CSF when administered intrathecally to healthy volunteersTo determine which modalities of pain are affected by treatment with Xen2174 when administered…
The objectives of the study are:To determine the pharmacokinetic and pharmacodynamic interaction of a single ascending dose of Xen2174 with bupivacaine, and in one cohort of Xen2174 alone, when administered intrathecally to healthy volunteers and…
To evaluate the overall safety and tolerability of intrathecally administered single ascending bolus doses of Xen2174 in healthy subjectsTo evaluate the effects of Xen2174, following its administration as a single intrathecal bolus, on EEG activity…
The aim of our study is to investigate the effectiveness of kinesio tape in patients with clavicle fractures in comparison to the standard treatment (with sling). Our main outcome is the NRS-pain score. Primary Objective: Is there a difference in…
This proof-of-concept study aims to non-invasively detect amyloid-beta (Aβ)-plaques in the retina of AD patients using a Heidelberg Spectralis scanner with Curcumin as labeling fluorophore. The retinal Aβ-plaques will be related to currently used AD…