9 results
Please refer to protocol, section 1.2 "Rationale"
To investigate the effects of 5 days of one legged knee immobilization with or without daily NMES on quadriceps CSA, lean mass and muscle fiber characteristics.
The aim of this study is to investigate the effect of a single bout of NMES on muscle protein synthesis rates in healthy elderly males.
To investigate whether twice daily local (calf muscle) NMES attenuates muscle loss during 2 weeks of unilateral ankle immobilization due to an ankle fracture.
The primary objective of the study is:* To demonstrate the reduction of low-density lipoprotein cholesterol (LDL-C) by evinacumab 15 mg/kg intravenously (IV) in comparison to placebo after 24 weeks in patients with homozygous familial…
The objective of this study is to assess the safety and effectiveness of the VENOVO * Venous Stent for the treatment of iliofemoral occlusive disease including Acute or Chronic Deep Vein Thombosis (DVT), May-Thurner Syndrome, or any combination of…
The primary objective of the study is to determine the proportion of patients with elevated TGs, without Familial ChylomicronemiaSyndrome (FCS) due to loss of function (LoF) mutations in lipoprotein lipase (LPL), and a history of…
PrimaryThe primary objective for Part A of the study is to assess the pharmacokinetics (PK) of evinacumab in pediatric patients with homozygous familial hypercholesterolemia (HoFH).The primary objective for Part B of the study is to demonstrate a…
The primary objectives of the study are- To evaluate the long-term safety and tolerability of evinacumab 15 mg/kg intravenous (IV) administered every 4 weeks (Q4W) in patients with homozygous familial hypercholesterolemia (HoFH).- To evaluate the…