3 results
The primary objective of this study is to obtain clinical proof of principle that the addition of a PgP/BCRP inhibitor increases CNS concentrations of tyrosine kinase inhibitors by inhibition of drug efflux transporter function in the blood brain…
*Run-in* part: The *run-in part* primary objective:• To determine a safe light dose for PC-A11 with interstitial laser light application in patients with recurrent head and neck squamous cell carcinoma unsuitable for surgery and radiotherapy and…
Determining a response characteristic of the vestibulocochlear nerve in healthy subjects (e.g. subjects without hearing loss or tinnitus), for the benefit of assessing possible aberrant characteristics in subjects with tinnitus, which data could be…