2 results
Approved WMOCompleted
The primary objective of this study is to obtain clinical proof of principle that the addition of a PgP/BCRP inhibitor increases CNS concentrations of tyrosine kinase inhibitors by inhibition of drug efflux transporter function in the blood brain…
Approved WMOCompleted
The primary objective is to determine an effect of sleep deprivation on CSF Aβ42 levels in humans.Secondary objectives: -Effect of unrestricted sleep on CSF Aβ42 levels.-Effects of unrestricted sleep and sleep deprivation on other known AD…