4 results
Here we will perform a proof of concept study on the ability of the antidepressant tianeptine to prevent respiratory depression from the opioid alfentanil in humans.
To establish the MaximumTolerated Dose, Dose Limiting Toxicities, and the safety profile of BMS-833923 administered in combination with cisplatin and capecitabine as first-line therapy. To describe preliminary evidence of tumor response as measured…
To assess whether tianeptine is able to antagonize opioid-induced respiratory depression.
Part A:- Evaluate the safety of increasing doses of a single dose continuous DMT infusion over 90 minutes in healthy smokers - Characterize the pharmacokinetics of a single dose DMT administered continuously over 90 minutes in healthy smokers -…