5 results
The objective of this study proposal is to determine whether pharmacologic optimization of voriconazole by means of therapeutic drug monitoring (TDM) results in improved patient outcomes (efficacy and safety) and is more cost-effective compared to…
The objectives are:1. the effect of steady state concentrations of voriconazole and fluconazole on the steady-state pharmacokinetics of TMC125,2. the effect of steady-state concentrations of TMC125 on the steady-state pharmacokinetics of…
Primary Objectives:• To assess the effects of VOR 200 mg BID on the steady-state PK of ATV administered as ATV/RTV300/100 mg QD in healthy subjects• To assess the effects of ATV/RTV 300/100 mg QD on the steady-state PK of VOR 200 mg BID inhealthy…
In this study, we will investigate how quickly and to what extent CKD 506 is absorbed, transported, and eliminated from the body. In addition, we will evaluate a possible interaction between CKD 506 and midazolam. We will do this by investigating…
This study aims to validate the efficacy of a wireless and small EMG sensor as a tool for monitoring asthmatic children. We will analyse differences in diaphragmatic muscle activity as measured with this EMG sensor before and after administration of…