6 results
The primary objective of the study is:* To demonstrate the reduction of low-density lipoprotein cholesterol (LDL-C) by evinacumab 15 mg/kg intravenously (IV) in comparison to placebo after 24 weeks in patients with homozygous familial…
Please refer to protocol, section 1.2 "Rationale"
The objective is to assess the safety profile of the hypothermic Airdrive* oxygenated machine perfusion system for graft preservation in kidney transplantation.
The primary objective of the study is to determine the proportion of patients with elevated TGs, without Familial ChylomicronemiaSyndrome (FCS) due to loss of function (LoF) mutations in lipoprotein lipase (LPL), and a history of…
PrimaryThe primary objective for Part A of the study is to assess the pharmacokinetics (PK) of evinacumab in pediatric patients with homozygous familial hypercholesterolemia (HoFH).The primary objective for Part B of the study is to demonstrate a…
The primary objective is to determine the survival rate after two and five years in fixed bearing Oxford lateral PKR with an uncemented femoral component and present patient reported outcome measures (PROMS), range of motion, radiographic findings…