3 results
Approved WMOPending
Aim of this study is to compare the effects of mannitol and HS in equimolar concentrations on cerebral blood flow, cerebral oxygenation, metabolism and inflammation in patients with severe TBI.
Approved WMOPending
The primary objective of this study is to assess the effectiveness and cost-effectiveness in terms of the number of surgeries prevented of a combination therapy versus usual care.The secondary objective of this study is to assess the effectiveness…
Approved WMOCompleted
Primary:To assess the safety and tolerability of MCLA-117, in order to determine the MTD/RP2D and frequency of administration.Secondary:- To assess the pharmacokinetic (PK) profile of MCLA-117 i.v. infusion- To investigate the pharmacodynamic (PD)…