9 results
The primary objective of this study is to evaluate the dose response, dose interval, efficacy, and safety of GSK961081 by studying three QD doses and three BID doses in subjects with COPD. The study will also evaluate the population PK, systemic PK-…
To compare the EPOS guideline with the free choice treatment of the GP for acute rhinosinusitis in general practice.
Primary:To compare the effect of UMEC/VI (62.5/25 mcg once daily) with UMEC (62.5 mcg once daily) on lung functionSecondary:To compare UMEC/VI, UMEC with salmeterol (50 mcg twice daily) on patient reported outcomes and on other COPD efficacy…
To demonstrate superiority of tiotropium vs. salmeterol in reducing exacerbations which are an important patient outcome because they are a major cause of morbidity from COPD. In addition, they are associated with a more rapid decline in lung…
Primary: Efficacy of FF/GW642444 100/25 mcg once daily in comparison with that of FP/salmeterol 250/50 mcg twice daily during 24 weeks.Secundary: Safety and tolerability.
With intervention with bronchodilators (usual care bronchodilators for COPD subjects), in one study histamine and in one study steroids, we want to investigate the respons on inspiratory lung function parameter like the FIV1 and also investigate…
Primary objectivesMeasuring the SARS-CoV-2-specific immune response against SARS-CoV-2 after inoculation with a single-dose Janssen compared to a homologous vaccination regimen with Janssen /Janssen and the comparison of a homologous vaccination…
Primary objectiveThe key objective is to examine the anti-body immune response to SARS-CoV-2 vaccination in shift workers, compared to dayworkers, Secondary objectives:• To tinvestigate whether sleep duration, independent of circadian misalignment,…
Key objective The key objective of the study to determine whether it is necessary to boost the healthy population in autumn. Primary endpoint: The primary endpoint is to determine the fold change in antibody level at day of boost and 28 days after…