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A Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Effect on
Seizures and Behavioral Symptoms of Multiple Individually Titrated Doses of Radiprodil
in Children with GRIN-related Disorder.

This study has been transitioned to CTIS with ID 2023-509672-42-00 check the CTIS register for the current data. Primary Objective:-To determine the long-term safety and tolerability of multiple individually titrated doses of radiprodil as an addon…

INFORM2 exploratory multinational phase I/II combination study of Nivolumab and Entinostat in children and adolescents with refractory high-risk malignancies

This study has been transitioned to CTIS with ID 2024-514409-78-01 check the CTIS register for the current data. Primary objectivePhase I (Phase I of the younger cohort was concluded in May 2023): To determine the recommended phase II dose (RP2D) of…