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The feasibility of a home-based remotely supervised maintenance exercise training program
in patients with COPD

To evaluate the safety, feasibility and efficacy of an 8-week remotely supervised home-based maintenance exercise training program following pulmonary rehabilitation in patients with COPD.

Treatment of Hemorrhoids: Rubber band ligation Or Sclerotherapy

We want to compare the effectiveness of sclerotherapy and rubberband ligation when it comes to symptoms. We will secondarily consider patient satisfaction, complications and recurrences. We hypothesize that both treatments are equally effective.

Is, in infertile women undergoing a basic fertility work-up, tubal flushing with oil-based contrast medium during hysterosalpingography (HSG) cost-effective compared to tubal flushing by hysterosalpingo-foam sonography (HyFoSy)? A randomized controlled trial.

The main objective of this study is to determine whether tubal flushing with oil-based contrast during HSG results into more pregnancies leading to live births when compared to tubal flushing with ExEm-foam during HyFoSy, and whether this approach…

Grip on knee Osteoarthritis; DIstraction Versus Arthroplasty (GODIVA) for young knee osteoarthritis patients in regular care.

To determine whether KJD is non-inferior on patient reported effectiveness as compared to a KP (i.e. usual care) for relatively young patients with end-stage knee OA. For the substudy: the primary objective is to predict the benefit from knee…

Beta-Alanine Supplementation in patients with COPD following a pulmonary rehabilitation program.

The primary objective is to compare the effects of daily beta-alanine supplementation or a placebo supplement on exercise tolerance (cycle endurance time).  The secondary objectives are:1) To compare the effects of daily oral beta…

The beneficial value of 18F FDG PET/CT in the follow-up of stage III non-small cell lung cancer patients

Primary Objective The primary objective of this study is to compare the 3-year overall survival of stage III NSCLC patients during follow-up surveillance with 18F FDG PET/CT versus follow-up with conventional CT surveillance. Secondary…

The prospective data collection initiative on on small bowel, colorectal and anal cancer - a prospective observational cohort study.

The main objectives of this project are:- To start a prospective observational cohort study of patients who have been diagnosed with CRC, small bowel and anal cancer and follow them from time of diagnosis until death.- To prospectively collect data…

Standardized dietary challenge to monitor effects of rehabilitation program in patients with COPD: a pilot study

In the present pilot study, we intend to test phenotypic flexibility (Phenflex)  in 20 clinically stable patients with COPD by exploring their response to a dietary challenge test before and after pulmonary rehabilitation. Moreover, the…

Early detection of diastolic dysfunction and heart failure with preserved ejection fraction

Which markers and which vascular calcifications can be used as diagnostic markers in the dectecion of heart failure with preserved ejection fraction and diastolic dysfunction. Diabetes is a progressive disease. We therefore expect…

Implementation of fluorescent imaging using indocyanine green to identify sentinel lymph nodes during surgery for breast cancer.

The INFINITE trail aims to successfully implement ICG-fluorescence for identifying the SLN by: 1) guiding the implementation process using the Effective Implementation of Change model developed by Grol and Wensing; 2) identifying and understanding…