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A web based cognitive behavioral therapy that addresses gender
dysphoria, gender minority stress and suicidality among gender minority youth. A Randomized Control Trial

Research question:To what extent is a web-based, Cognitive Behavioral Therapy (CBT) specially designed for young gender diverse youth in the Netherlands, an effective treatment to reduce their suicidality? Are there gender, sex assigned at birth,…

Laparoscopic versus robot-assisted left-sided pancreatectomy for benign and pre-malignant lesions (DIPLOMA-3): an international multicenter patient-blinded randomized controlled trial

To compare L-MILP with R-MILP for benign and pre-malignant lesions of the pancreas in high-volume centers, regarding:1. Peri- and postoperative outcomes in terms of COMPOS-panc left score, for non-inferiority2. Total hospital-related costs, for…

Online medical hypnosis exercises to improve mental health in primary school children and prevent future mental health issues.

The primary objective is to study the effect of daily listening for 6 weeks to the Breinbaas hypnosis recordings on self esteem compared to controls. Secondary objective(s) are studying the effect of daily listening to the Breinbaas hypnosis…

ExerciseEnhances+: A prospective cohort study on the synchronization of exercise therapy and cognitive behavioural therapy in depression

This study will assess the effect of combining exercise therapy with CBT 12-16 weeks and explore the mechanisms underlying exercise*s mood- and plasticity-boosting effects. The primary question is whether a higher dose of exercise leads to faster or…

A performance evaluation study for the testing of DNA extracted from tumor tissue samples, using the therascreen® KRAS RGQ PCR Kit, from participants with Non-Small Cell Lung Cancer in Lilly*s Clinical Trial (Protocol No. J3M-MC-JZQB/ SUNRAY-01) in order to generate data to demonstrate the performance of the kit as a CDx.

For Lilly's study (drug study)Primary Objectives:Dose Optimization- To determine the optimal dose of LY3537982 (50 or 100 mg BID) to be administered in combination with pembrolizumabSafety Lead-In- To determine the dose of LY3537982 to be…