213 results
Primary Objective• To validate the existing demarcation formula (consisting of psychometric and biological markers) which predicts the sensitivity to Lybrido or Lybridos in women with female sexual interest/arousal disorder (FSIAD with or without…
The primary objective is to assess the contribution of HER2-PET to subsequent anti-HER2-therapy decisions. Secondary objectives are assessment of clinical value of HER2-PET for the referring clinician; correlation of HER2-PET with standard…
Is ductoscopy with white light and autofluorescent light a useful method for diagnosing precancerous breast lesions?
The main objective of this study is to assess the effects of rituximab (RTX) as a rescue therapy for therapy resistant progressive IMID- IP patients. Specifically there is an objective assessment of (1) pulmonary function tests (PFTs) and (2)…
Aim of the present study is to investigate if a combination of a radioactive and fluorescent tracer can increase the sensitivity and specificity of the SLNM technique in colon and rectal cancer by utilizing the radioactive component for preoperative…
Treatment strategy in early HCC aims at the local removal of the tumor and represents a potentially curative treatment option (resection, liver transplantation, PEI, RFA, BT). Patients in intermediate and advanced stage of HCC receive treatment with…
The principal objective of the study is to determine if the performance of the new technique (magnetic tracer and magnetometer) is equivalent to the performance of the standard technique (patent blue dye and radioistope; or radioisotope alone). The…
1. The primary aim of the proposed research is to compare the value of current best available imaging method (PET-CT) with recently evolved functional imaging with DWI-MRI alone or in combination with PET/CT in determining response to neo-adjuvant…
The primary objective is to compare GLP-1R-imaging to standard imaging techniques now used in pre-operative imaging of patients with AHH. All patients will undergo the standard imaging procedures of the specific centre and in addition we will…
1. To study the safety and feasibility of para-aortic surgical staging in advanced cervical cancer in the Netherlands.2. To provide insight in the possible effectiveness of para-aortic surgical staging in advanced cervical cancer as compared to…
Primary Objective: The primary objective is to determine whether the administration of Gelofusine will reduce the kidney uptake of 111In-labeled exendin in humans by enhancing the excretion of 111In-labeled exendin. These highly relevant data can…
Question: Is it an added value for the patient if there will be a default capsaicin provocation test to diagnose chronic cough?It will be investigated or with the aid of the capsaicin provocation test the diagnosis sensory hyperreactivity (SHR) can…
The primary aim of this study is to determine whether the biomarkers PCA3, TMPRSS2-ERG and the NovioGendix prostate cancer biomarker panel (NGMP) are, by themselves or as a panel of biomarkers, a reliable predictor of survival in men with CRPC…
The primary objective is to evaluate the clinical utility of experimental PET scans, in the setting of metastasized breast cancer (MBC) at first presentation. Secondary objectives: - The relation between progression free survival (PFS, defined as…
The main objective of this study is to depict microglial activation behind a closed BBB in vivo and possibly establish an imaging marker of fast clinical progression, we will aim at visualizing microglial activity in vivo in cortical and hippocampal…
To evaluate the effectiveness of the Chartis System in selecting subjects with heterogeneous emphysema who will achieve Lung Volume Reduction from Endobronchial Valve therapy.
This study consists of two phases. For more information about the study layout, see page 13-16 of the research protcol.The aim of phase 2:- To compare two different sentinel node techniques in patients, suspicious for endometrial cancer. The main…
This investigation aims to test a new, better and faster method voor measurement of the LVEF, that does not depend on technetium. The method relies on the tracer Gallium-citrate, a well-known molecule that is available in unlimited quantities in-…
By adding Cetuximab to standard treatment, we hope to prolonge progression free survival
To evaluate if 11C-PiB is able to detect amyloid deposits in affected other organs and tissues in patients with systemic amyloidosis and to correlate the uptake of 11C-PiB in the different organs to laboratory parameters, biopsies and other imaging…