349 results
In the PROHTECT-3 trial, we offer hrHPV testing on self-sampled (cervico-)vaginal specimens obtained by a lavage device. The sensitivity and specificity for high grade CIN and cervical cancer (CIN2+/CIN3+) of two triage strategies of hrHPV positive…
There have been several studies that showed a possible positive effect of electrical stimulation on wound healing. One of the working principles is increasing blood flow. This could mean that by giving frequent electrical stimulation on the foot and…
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
The scientific hypothesis of the present study is that supervised implementation of the guideline “Oral health care in (residential) care homes for elderly people” is more effective in improving oral health and oral health care of the residents when…
Flumazenil is a substrate of P-glycoprotein at the blood-brain barrier.
Our hypothesis is, that the extrinsic mechanism in the etiology of SIS is only valid for a subgroup of patients; complaints of SIS can be caused by 1) a pathologic pattern of arm-scapula movements caused by a disrupted balance in muscle forces,…
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1. To determine the reproducibility and sensitivity of the Energy Cost of Walking test (ECWT) in boys with Duchenne muscular dystrophy, in comparison with the reproducibility and sensitivity of the 6-Minute Walk Test (6MWT); 2. To evaluate the 1-…
A postoperative retransfusion system is most effective in terms of allogeneic blood transfusion rates when in situ for maximum of 6 hours after major orthopaedic surgery.
We hypothesize that exogenous, enterally provided glutamine contributes substantially to the de novo synthesis of arginine in critically ill patients.
By sufficient electrical stimulation of the ampullary nerves, a congruent vestibulo-ocular reflex will occur.
(Short) stay and, if possible, treatment at the PMU, will give an improvement in regular psychometrics or at least in some of them.
In general practices, proactive care for potentially frail older people with the use of Utrecht Periodic Risk Identification and Monitoring (UPRIM) and the use of a Geriatric Nurse Primary Care (GNPC) will result in better daily functioning in…
Previous randomised trials have shown the efficacy of etanercept in RA patients. In this study we will evaluate the respons of etanercept in anti-TNF naive patients compared to patients who have failed other anti-TNF. We will look for clinical…
Two hypotheses will be tested. First, we expect parents in the experimental group, who drink as well as those who abstain from alcohol, to use more alcohol-specific socialization strategies than parents in the control group. Second, we expect that…
Patients with a wrist trauma represent a substantial part of the patient population at the Emergency Department. Most hospitals routinely carry out a radiological examination of patients following wrist trauma to exclude a distal radius/ulna…
Missing doses and early discontinuation are two levels of inadequate drug adherence. Multidisciplinary interventions may improve adherence. We hypothesize that in patients with multiple sclerosis (MS) certain modalities or durations of care are…
Tolerance of the new paediatric sip feed is equal to the standard paediatric sip feed.
By injection of triamcinolone before dilation we hypothesise that the time to repeat dilation is increased and the total number of dilation sessions is decreased as well.
Collect long term data on compliance and safety of the study product in patients with mild Alzheimer’s disease who completed the Souvenir II study.