373 results
Objective: 1. To determine protein balance in septic, critically ill children at baseline and during a Hyperinsulinemic Euglycemic Clamp, while receiving standard or high protein intake based on age group; 2. To assess insulin sensitivity and…
We hypothesize that induction of labour in patients with gestational hypertension, deteriorating chronic hypertension or preeclampsia between 34 and 37 weeks reduce the maternal morbidity but might increase the RDS rate in neonates, compared to…
Cap-assisted colonoscopy may improve the adenoma detection rate in CRC screening participants.
We expect (in the intervention condition as opposed to the control condition): 1. A decrease in children's emotional/behavioral problems and rule-braking behavior; 2. An increase in on-task behavior and teacher's well-being; 3.…
It is expected that the drink will contribute to an improved postprandial glycaemic response and to an increase of satiety in subjects with type 2 diabetes mellitus.
To investigate the difference in effectiveness of methylphenidate (MPH) in the treatment of adult ADHD patients with and without comorbid cocaine dependence.
Pain (physical discomfort) and challenging behavior are highly prevalent in nursing home residents with dementia. It has been shown that pain is undertreated in this group, and that psychosocial interventions for behavioral problems are, allthough…
In the Netherlands over 10.000 patients are diagnosed with head and neck cancer or lung cancer every year of whom 25-50% have comorbid anxiety or depression. Is a stepped care strategy applied in an oncological setting more (cost-)effective to…
This study aims to answer two research questions: 1. Does web-based monthly monitoring using the Asthma Control Test (ACT) improve asthma control? Is this strategy cost-effective? 2. Does asthma management guided by the fraction of nitric oxide in…
The extrahepatic bile ducts may be visualized during cholecystectomy using a near-infrared fluorescence camera and an injection of indocyanine green into the gallbladder.
Salmeterol has an inhibitory effect on both allergen and allergen/LPS induced inflammation in asthmatics while on maintenance treatment with low dose corticosteroids.
This international, multi-centre, double blinded, placebo-controlled, randomised clinical trial will be performed: To assess the effectiveness of one year of alternate days Levamisole treatment in a dose of 2.5 mg/kg in the prevention of relapses…
COMT and/or PRODH polymorphisms are debt to cognitive deterioration in velocardiofacial syndrome.
A higher orosensory exposure will lead to earlier sensory satiety, resulting in a lower intake of the test food; and in a better learning of energy content, resulting in intake adjustments for energy.
1. Null hypothesis (H0): PFS at 1 year after start lenalidomide maintenance = 59%; 2. Alternative hypothesis (H1): PFS at 1 year after start lenalidomide maintenance = 75%.
The following hypothesis will be made: 1. P0 is the largest OS probability at 9 months which, if true, implies that the therapeutic activity of that regimen is too low. In the present trial, P0 has been taken as 35%; 2. P1 is the lowest OS…
Objectives: 1. To investigate the added effects of eplerenone on top of ACEi, with and without dietary sodium restriction, on residual albuminuria, hypertension, and tubular injury markers, in patients with diabetic nephropathy; 2. To investigate…
To visualize the tumor and to study normal tissue biodistribution and pharmacokinetics of radiolabeled TRM-1.
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1. Hoofdpijn komt vaker voor bij corticale infarcten en vertebrobasilaire infarcten dan bij lacunaire infarcten; 2. Infarcten in de posterieure circulatie veroorzaken vaker hoofdpijn; 3. Patiënten met hypertensie hebben minder vaak hoofdpijn dan…