612 results
Non-inferiority trial in order to evaluate the effectiveness of the new compound (recombinant human hyaluronidase or Cumulase®), effectiveness being defined by intactness after ICSI and fertilization rate.
Objective: 1. To determine protein balance in septic, critically ill children at baseline and during a Hyperinsulinemic Euglycemic Clamp, while receiving standard or high protein intake based on age group; 2. To assess insulin sensitivity and…
We hypothesize that induction of labour in patients with gestational hypertension, deteriorating chronic hypertension or preeclampsia between 34 and 37 weeks reduce the maternal morbidity but might increase the RDS rate in neonates, compared to…
Cap-assisted colonoscopy may improve the adenoma detection rate in CRC screening participants.
We expect (in the intervention condition as opposed to the control condition): 1. A decrease in children's emotional/behavioral problems and rule-braking behavior; 2. An increase in on-task behavior and teacher's well-being; 3.…
Standard localized ligations are as feasible as doppler-guided ligations of hemorrhoid arteries.
Frequently people experience nausea and vomiting following surgery. There are several pharmacologic interventions possible; there is no rational evidence-based approach available. In this study the current therapy regaring PONV and its efficacy in…
incomplete
The nurse practitioner will actively approach all fracture patients above the age of 50 for screening and intensive treatment of osteoporosis. This will improve the number of fracture patients screened and treated for osteoporosis.
It is expected that the drink will contribute to an improved postprandial glycaemic response and to an increase of satiety in subjects with type 2 diabetes mellitus.
To prospectively assess the efficacy of combined pan-chromoendoscopy and confocal colonoscopy for the detection of neoplastic lesions in patients at high-risk for CRC. Two issues will be addressed: 1. Does pan-colonic chromoendoscopy improve the…
It is our hypothesis that a combined life style intervention of exercise and weight loss will result in a reduction of pain and improvement of function of the affected hip joint, which will postpone a chirurgical intervention.
The vesselseal instrument results in shorter operating time and less intraoperative bloodloss than the conventional bipolar coagulation in patients undergoing laparoscopic hysterectomy and/or salpingo-oophorectomy
To investigate the difference in effectiveness of methylphenidate (MPH) in the treatment of adult ADHD patients with and without comorbid cocaine dependence.
Donor-specific antibodies form a significant barrier in transplantation of highly pre-sensitized dialysis patients. Increased waiting time is associated with increased morbidity and mortality among these patients. Thus, there is a need to further…
Pain (physical discomfort) and challenging behavior are highly prevalent in nursing home residents with dementia. It has been shown that pain is undertreated in this group, and that psychosocial interventions for behavioral problems are, allthough…
The EEG profile in responders to methylphenidate will be differ from the EEG profile in non-responders to methylphenidate (i.e. higher total power, increased theta/beta ratio and theta/alpha ratio).
In the Netherlands over 10.000 patients are diagnosed with head and neck cancer or lung cancer every year of whom 25-50% have comorbid anxiety or depression. Is a stepped care strategy applied in an oncological setting more (cost-)effective to…
Early PEG placement in ALS patients with dysphagia is associated with longer survival, better nutritional and functional status, and better quality of life
This study aims to answer two research questions: 1. Does web-based monthly monitoring using the Asthma Control Test (ACT) improve asthma control? Is this strategy cost-effective? 2. Does asthma management guided by the fraction of nitric oxide in…