503 results
The aim of this study is to determine whether multiparametric MRI (mpMRI) of the bladder, in combination with an outpatient biopsy for histological confirmation, is a faster, safer, cheaper and therefore more cost-effective way to detect or…
Does mindfulness based cognitive therapy in addition to treatment as usual (TAU) improve QoL compared to TAU alone in patients with CPP based on a hypertonic pelvic floor ?
Primary objective: To validate the new, non-invasive QP-CMR imaging, stress T1 mapping reactivity and OS-CMR imaging with breathing maneuvers against invasive gold standard FFR for detection of obstructive CAD.Secondary objectives: 1) To compare (…
The objective of this study is to prospectively compare decongestive therapy administered by the Reprieve DMS system to Optimal Diuretic Therapy (ODT) in the treatment of patients diagnosed with acute decompensated heart failure (ADHF). The main…
We will measure correlations between serially measured MRI parameters (pretreatment and early during treatment) and therapy outcome (response, locoregional recurrence and overall survival) in patients with HNSCC undergoing chemoradiation (CRT)…
This research aims to examine the feasibility of home monitoring of serum uric acid for both patients and stakeholders, using a digital home measuring device in conjunction with a nurse-led T2T approach.Primary research question:What is the…
Objectives:The main objective will be to assess whether treatment with nVNS, LXB or both interventions will increase the clearance of Aβ from the brain, compared to pre-treatment, in patients with CAA. Second objective is to study whether CAA…
see also aboveThe aim of the project is to investigate the effects of an accessible 20- and 50-week walking intervention for people with diabetes. This examines the level of physical activity, quality of life, patient activation, diabetes self-…
To investigate the impact of BT as compared to standard of care in severe asthma patients that remain uncontrolled despite standard treatment including adequate doses of inhaled preventer therapies with or without biologics on:(1) rate of…
To assess the rate of major adverse cardiac and cerebrovascular events (MACCE) between patients with and without coronary microvascular disease (CMD) based on Microvascular Resistance Reserve (MRR) at 1 year follow-up.
The main objective of this study is to establish the efficacy of *pit picking with laser therapy* versus *pit picking alone* on both short and long-term outcomes.
1. At 1 year, to demonstrate non-inferiority for target vessel failure (TVF) of a treatment strategy with first line SELUTION SLR* DEB + provisional DES vs. systematic treatment with DES for the treatment of de novo coronary lesions.2. At 5-year…
To characterize the phenotype, function and gene expression profiles of immune cells and hepatocytes in blood and liver of patients with chronic hepatitis D.
To assess the ability to track blood pressure decrease measured by the Corsano CardioWatch 287-2 after a period of 28 days of antihypertensive drug treatment initiation, uptitration or change in antihypertensive drugs.
Primary objective: To quantify the degree of respiratory muscle degeneration and dysfunction using ultrasound in patients with DMD over a wide age range; from early childhood to adults.Secondary objective: To determine the association between…
To investigate the production of sufficient numbers of effective CAR/CCR T-cells with T-cells obtained from blood of MM patients.
The overall objective of this study is to develop and evaluate an optimized dosing algorithm (CT-CL) for carboplatin using serum creatinine and CT-derived body composition that can be easily implemented in clinical practice.
Primary Objective: Is the intervention model feasible and acceptable for clients, parents/caregivers, peers and therapists?Secondary Objective(s): 1) Establishing first evidence of efficacy of peer-mentored CBT in reducing anxiety in adolescents…
To assess the effects of anesthetics on local (cerebral) microvascular parameters in craniotomy patients. Secondary objective: To assess the effects of anesthetics on systemic (sublingual) microvascular parameters in craniotomy patients.
In the current study, the subjective and objective effectiveness of cognitive rehabilitation therapy for people with somatic symptom and related disorders will be investigated. Additionally, the effects of this treatment on brain activity in the…