850 results
In patients diagnosed with a hip fracture who also have acute myocardial injury on presentation to hospital, is accelerated surgery superior to standard care for the primary outcome of death at 90 days after randomization?
The aim of this study is to determine whether multiparametric MRI (mpMRI) of the bladder, in combination with an outpatient biopsy for histological confirmation, is a faster, safer, cheaper and therefore more cost-effective way to detect or…
The primary objective of this study is to investigate the feasibility of a multimodal prehabilitation programme consisting of MIET during neoadjuvant intravenous chemotherapy infusion, HITT and strength training during the last six weeks prior to…
To study the impact of addition of the GAAD score to imaging in patients with chronic liver disease eligible for HCC surveillance.
To investigate the feasibility of Bergström needle biopsies of the vastus lateralis muscle, and NIRS measurements of the gastrocnemius muscle in post-ICU patients.
Primary objective: To assess the impact of acute laser treatment on muscle tissue mitochondrial respiration in vivo in healthy, young adults. Secondary objective: To assess the impact of acute laser treatment on muscle cellular energy, anabolic,…
The primary objective of this clinical feasibility study is to assess the overall diagnostic yield of the Investigational Device in comparison to standard care. The secondary objective is to assess the safety issues that possibly occur while using…
Primary objective:- To study the impact of community acquired pneumonia in children on persistent symptoms and quality of life, from admission in hospital until one year after discharge.Secondary objectives:To investigate/assess:- The association…
The objective of this pilot study is to evaluate the effects of separate individualization of the AFO stiffness towards plantar- and dorsiflexion in a spring-hinged NEURO SWING AFO compared to a spring-like AFO without hinge (3 types) having the…
Hypothesis: implementation of individualized, integrated 7 Tesla MRI and MEG brain networks can increase the effectiveness of DBS by improving motor symptoms and quality of life in patients with Parkinson's disease and essential tremor.…
The aim of the current study is to determine the transport functionality, integrity, and viability in intestinal tissue obtained from patients who are expected to have a disturbed intestianl functionality due to severe obesity.
We will assess safety (potential adverse events related to phototherapy using Jauni, e.g. skin injuries, hyperthermia, or hypothermia) and effectiveness (e.g. rate of lowering of bilirubin levels, duration of phototherapy need) of phototherapy using…
To assess the effectiveness of EMDR in RA patients with persistent pain despite inflammation being under control.
Investigating the function of monocytes and their precursor cells originating from circulation, bone marrow, and spleen in the context of ovarian cancer.
In the current study, we aim to assess the energy requirements of professional football players during different phases in the rehabilitation from an ACL reconstruction. As such, this study will identify the energy and nutritional requirements,…
This proposal aims to evaluate the use of STE as a diagnostic tool for early diagnosis of impaired fetal growth in twins. The results from this proposal will be beneficial from a public health perspective, as it will lead to accurate and early…
The overall aim of this project is to unravel the role of IFN-I in ILD in the known/classified SADs and in ILD with autoimmune features but without a specific SAD diagnosis (IPAF), with as ultimate goal better treatment. Since 13-40% of ILD patients…
To evaluate the efficacy of SBRT as additional treatment after standard care chemotherapy regarding tumor local control, toxicity, progression-free survival, overall survival and quality of life. In addition, to explore the value of immunodynamics…
Hand function impairment in systemic sclerosis: Outcomes, Mechanisms and Experience (HANDSOME) study
Primary Objective: Determination of risk factors for hand function impairment in systemic sclerosis (SSc) patients with early disease, very early disease and established hand impairment (contractures) at 2 years follow-upSecondary Objective(s):-…
The primary objective is to characterise and understand the heterogeneity in patients with ME/CFS (i.e. comorbidities, variability in symptoms and disease progression, severity, and cognitive and autonomic impairment). Therefore, the secondary…