49 results
No hypothesis due to the explorative character of the study
To evaluate the real-world use and effectiveness of anti-IL-5 biologics (mepolizumab, reslizumab and benralizumab) in patients with severe eosinophilic asthma with comorbid bronchiectasis
We hypothesize that lung ultrasound is an adequate diagnostic modality using thoracic CT as reference standard. i.e. a sensitivity and specificity for all diagnoses above 70%.
The aim of the study is to investigate the effect of magnetic resonance (MR) based online adaptive radiotherapy (RT) for treatment of low to intermediate risk localized prostate carcinoma (PCa) on the radiotherapy dose on the prostate and organs at…
With this study we expect to generate important knowledge about treatment experience, treatment adherence, and quality of life of children using TAI with a Navina system. If we can identify factors that affect either one of those, pediatric…
Our hypothesis is that time to complete wound healing in patients with a POWI who receive NPWTi will be shorter than in patients receiving standard wound care (i.e., NPWT and/or conventional wound care). We do not expect that NPWTi pose an extra…
Child aged 3 to 9 years old suspected of child sexual abuse (CSA)
At two-year follow up, employees of the intervention schools report significantly lower levels of work stress and work stress risks as compared to employees of the control schools
It is hypothesized that CATs and PROMIS short-forms have higher measurement precision and smaller measurement error (better detectable change) as compared to currently used PROMs.
It is hypothesized that measurement of CO, SV and LVEF with the Lumify/DIA system corresponds with CO, SV and LVEF measurements with conventional non-automated echocardiography.
The goal of EEG4STROKE is to test a device that enables paramedics to accurately diagnose patients with suspected stroke on site (in the ambulance or living room of the patient). EEG4STROKE will integrate hardware and software to triage stroke…
Diaphragm thickness is constant throughout the zone of apposition in craniotomy-caudal direction
Emerging techniques measuring oxidative APAP metabolites and microRNA-122 (miR-122) could make it possible to detect paracetamol induced liver injury earlier and more precisely than currently used paracetamol plasma concentrations and clinical…
We hypothesize that the MACE and mortality rates will be very low, due to mild or absent coronary disease on the CCTA and the short follow-up duration.
Primary hypothesis: An extension of the psychotherapeutic treatment concept by animal-assisted group therapy (plus treatment as usual / TAU) lowers depressive symptomatology, possibly via increases in patients' experience of self-efficacy and…
We hypothesize that CBFV measurement in the ICA and pACA using Doppler CUS will become a monitoring technique to guide optimizing cerebral perfusion in the perioperative phase. Furthermore, HFR Doppler CUS will provide additional quantitative…
We hypothesize that the combination of LFPs (recorded with implanted DBS electrodes) and resting state fMRI and 64-channel EEG can provide insight in the thalamocortical coupling and other brain circuits involved in the disturbed brain dynamics in…
Data extraction with CDC to study the effectiveness of Novasure endometrial ablation is reliable compared to manual EHR data extraction
1/2. Postoperative infections are a risk factor that negatively interferes with physical recovery 1 year after cardiac surgery. It is expected that propensity scoring techniques will provide a more accurate (“unbiased”) estimate of the effect of the…
The clinical efficacy of CFTR modulating drugs is limited, some patients respond, while others do not or have side effects. The inter-individual variability (IIV) in the PK seems large, and therefore we hypothesize that we might be over- or…