116 results
Primary Objectives: To evaluate the status of the circadian rhythm of critically ill children in multiple facets and on multiple moments during their PICU stay. To describe the distributions of rhythmic parameters in the paediatric ICU and their…
a) To determine the occurrence of subclinical and clinical disease and transmission of SARS-CoV-2 in families with children aged 14-18 years; and b) to examine the associations of socio-demographic and lifestyle, genetic, and epigenetic factors with…
Primary ObjectiveTo evaluate whether lenvatinib in combination with ifosfamide and etoposide (Arm A) is superior to ifosfamide and etoposide (Arm B) in improving progression-free survival (PFS) by independent imaging review [IIR] using Response…
To collect reference data of dEMG in neonates to use for testing the Bambi Belt B.V. algorithm which is under development.
Investigate regulators of (disturbed) iron homeostasis and cellular determinants of iron overload in RHA. to decipher crucial elements of the crosstalk between iron metabolism and erythropoiesis
In this explorative study, we aim to:• Analyze neoantigens expressed on different tumors of CMMR-D patients, to identify possible target antigens for DC vaccination studies.• Investigate the presence of pre-existing immune responses against…
INCbase is a research platform to collect prospective standardized longitudinal data from a worldwide population of patients with suspected CIDP. One of the first objectives of the Inflammatory Neuropathy Consortium Base (INCbase) is to develop a…
Primary Objective: To assess the agreement between the heart rate assessed with a dedicated cap with integrated PPG-leads and standard ECG monitoring using regular neonatal thoracic electrodes as reference technique.Secondary objectives:Does…
Objectives: 1) Assess neural and cognitive biomarkers (through eye-tracking, EEG/ERP and cognitive measures) in a community sample of infants at heightened non-familial risk for ASD and in age and gender matched low-risk controls. The HR group is…
1. To investigate the feasibility to perform advanced echocardiographic measurements2. To describe the incidence and variation of cardiac damage during and shortly after treatment using detailed advanced echocardiographic measurements and ECG at…
This study has been transitioned to CTIS with ID 2024-513070-21-00 check the CTIS register for the current data. Primary objectives: Improvement of CR2 rates after induction with ALL R3 with bortezomib versus withoutbortezomib in HR relapsed ALL…
To determine the differences in muscular activity of the diaphragm between children with controlled asthma, uncontrolled asthma, dysfunctional breathing patterns and healthy children.
Primary objective: To determine diaphragm thickness and thickening fraction in healthy children below or equal to 8 years of age.Secondary objective: To determine the interrater reliability of operators performing the ultra-sound
The objective of this explorative study is to determine the feasibility of measuring dEMG with a belt in preterm and term born infants during routine caregiving. Feasibility is confirmed when heart rate and respiratory rate reach a predefined level…
The objective is to examine how working memory functioning in children with ADHD and/or ASD as measured with the Lion game and the Monkey is influenced by context and to assess the diagnostic utility and ecological validity of the Lion and Monkey…
To objectively determine the severity of CTD related physical impairments, complaints and difficulties during participation in daily life activities. An additional study objective is: - To determine risk factors for the development of health…
To determine the feasibility of umbilical PO for HR measurements after cord clamping in infants needing stabilization at birth and to compare this with standard PO on the right hand.
Objective: The aim of this study is to define: i. the environmental and biological factors that drive skin sodium accumulation according to the novel 3-compartment concept in the skin of children; ii. whether these factors are associated with risk…
This research aims to investigate imaginary rescripting (ImRs) as a 'stand alone' intervention in clients aged eight to twelve years, in which bullying experiences have led to complaint behaviour (emotional problems, depressive complaints…
The overall goal of this study is to get an up-to-date data on the incidence, disease burden, and etiology of gastrointestinal infections in the general practitioner population. More specific goals:1. Determine the incidence of gastrointestinal…