3159 results
To identify novel childhood osteosarcoma predisposing genes.
Determination of microbiological, macro and microscopic / histological characteristics after RYGB, mainly targeted at identifying inflammatory characteristics, bacterial (over) growth and / or atrophy / metaplasia in the excluded stomach and the…
To determine whether the adapted Sternberg short-term working memory task (STMST) is an effective method to induce emotional stress-induced malodour.
The purpose of the study is to investigate how quickly and to what extent 2 different production batches of FT218 (batch A and batch B) are absorbed and eliminated from the body (this is called pharmacokinetics). In this study it is investigated…
We propose an observational clinical trial in critically ill patients to investigate the effect and duration of platelet transfusion on coagulation, including platelet function and markers of endothelial activation in critically ill patients.
The primary objective is to evaluate plasma levels of A*1*42/A*1*40 ratio, A*1*40, A*1*42, neurofilament light (NFL), t*tau and anti*tau antibodies as disease*specific markers for AD. The secondary objective is to measure biological age parameters (…
The purpose of this study is to investigate how quickly and to what extent PF-06650833 is absorbed, distributed, metabolized (broken down) and eliminated from the body (this is called pharmacokinetics). PF-06650833 is not registered as a drug, but…
- To evaluate the pharmacokinetic (PK) profile of the combination of GLPG3067, GLPG2222, and GLPG2737 following repeated morning versus evening doses given to healthy female subjects - To evaluate the safety and tolerability of the combination of…
To investigate feasibility, safety and toxicity as well as immune-response of an allogeneic tumor cell lysate (PheraLys) loaded onto autologous dendritic cells (MesoPher) in resected pancreatic cancer patients who received adjuvant standard of care…
The purpose of the study is to investigate how quickly and to what extent BAY 1834845 is absorbed and eliminated from the body (this is called pharmacokinetics). In both study parts it will also be investigated to what extent BAY 1834845 is…
1) To determine the effect of the level of voluntary force on the magnitude of superimposed twitches evoked using peripheral nerve stimulation (PNS), motor point stimulation (MPS), and transcranial magnetic stimulation (TMS) in first dorsal…
* Primary Objective: determine the functional outcome and clinical efficacy after open surgical implantation of the Ankle Spacer for patients with large, cystic, previously surgically failed and/or multiple OCDs of the talus by means of functional…
To identify the pathophysiology and predictors of study (extreme) cancer treatment -induced cardiovascular toxicity in cancer patients, by in vitro investigation of cardiovascular toxicity in patient-derived cardiomyocytes (iPSC-CMs) and endothelial…
To evaluate the effect of Eye Movement Desensitisation and Reprocessing (EMDR) as an alternative or additional therapy for misophonia.
to establish primary patient derived organoid cultures from GM to study mechanisms that contribute to aggressive tumor growth and treatment resistance in primary and recurrent GM.
Collect data to determine whether early pimple markers can be identified using images and a skin expert review or algorithm for at least 1 day before they are visible (visible or tangible) for the subject (self-detection).
To assess if the irradiation of 2MED UVB induces a significant level of hyperalgesia to be used in the UVB pain model
Primary Objective: To establish the effect of asymmetrical guidance provided by the Lokomat exoskeleton on levels of muscle activity in persons with post stroke hemiparesis. Secondary Objective(s): (i) To establish if the abovementioned effects (see…
Primary objective To assess accuracy of GCCGM vs FLFM in 18 subjects with diabetes during a 6 day mountainbike tour in the AlpsSecondary objectives To assess the (differences in ) time in hypo-, normo- ,and hyperglycemia (expressed in minutes per…
* To determine the minimum effective dose of 5-aminolevulinic acid (Gliolan) for adequate MitoPO2 measurements during upper endoscopy.