207 results
In the PROHTECT-3 trial, we offer hrHPV testing on self-sampled (cervico-)vaginal specimens obtained by a lavage device. The sensitivity and specificity for high grade CIN and cervical cancer (CIN2+/CIN3+) of two triage strategies of hrHPV positive…
There have been several studies that showed a possible positive effect of electrical stimulation on wound healing. One of the working principles is increasing blood flow. This could mean that by giving frequent electrical stimulation on the foot and…
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
The scientific hypothesis of the present study is that supervised implementation of the guideline “Oral health care in (residential) care homes for elderly people” is more effective in improving oral health and oral health care of the residents when…
Flumazenil is a substrate of P-glycoprotein at the blood-brain barrier.
Our hypothesis is, that the extrinsic mechanism in the etiology of SIS is only valid for a subgroup of patients; complaints of SIS can be caused by 1) a pathologic pattern of arm-scapula movements caused by a disrupted balance in muscle forces,…
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1. To determine the reproducibility and sensitivity of the Energy Cost of Walking test (ECWT) in boys with Duchenne muscular dystrophy, in comparison with the reproducibility and sensitivity of the 6-Minute Walk Test (6MWT); 2. To evaluate the 1-…
A postoperative retransfusion system is most effective in terms of allogeneic blood transfusion rates when in situ for maximum of 6 hours after major orthopaedic surgery.
By sufficient electrical stimulation of the ampullary nerves, a congruent vestibulo-ocular reflex will occur.
Previous randomised trials have shown the efficacy of etanercept in RA patients. In this study we will evaluate the respons of etanercept in anti-TNF naive patients compared to patients who have failed other anti-TNF. We will look for clinical…
Patients with a wrist trauma represent a substantial part of the patient population at the Emergency Department. Most hospitals routinely carry out a radiological examination of patients following wrist trauma to exclude a distal radius/ulna…
Missing doses and early discontinuation are two levels of inadequate drug adherence. Multidisciplinary interventions may improve adherence. We hypothesize that in patients with multiple sclerosis (MS) certain modalities or durations of care are…
Tolerance of the new paediatric sip feed is equal to the standard paediatric sip feed.
Collect long term data on compliance and safety of the study product in patients with mild Alzheimer’s disease who completed the Souvenir II study.
the aim of this study is to compare two strategies that present a large contrast in the stimulation dosage, i.e. a high dosage of stimulation versus a low dosage of stimulation. Our study is designed to objectively compare the ongoing pregnancy rate…
Current methods of detecting the presence and/or prognosis of prostate cancer are not optimal. New markers will provide better detection and/or better methods to determine prognosis. In addition, there are currently no methods available to properly…
Idiopathic Parkinson's Disease is a chronic progressive neurodegenerative disorder. The preclinical phase of the disease is accompanied by different motor and non-motor symptoms and signs. These symptoms can occur even 5-8 years before…
Comparison between surgical vs non surgical treatment of an atraumatic cuff rupture.
Shoulder load and daily activities compared between power assisted and manual wheelchair propulsion.
Because the force needed to propel the wheelchair is partly delivered by a motor, we hypothesized that the forces and moments exerted on the rim will decrease. Consequently, forces and moments at the glenohumeral joint and muscle activation of push…