12 results
Primary Objectives:Associated pharmaceutical trial:To compare the efficacy of disitamab vedotin in combination with pembrolizumab to chemotherapy as first-line treatment in participants with advanced UC that expresses HER2Clinical…
The goal of the current observational multicenter pilot study is to investigate if an 8-week Acceptance and Commitment group therapy for youth with ASD is an effective intervention to increase adaptive emotion regulation, psychological flexibility…
The aim of this study on the one hand is to gain insight into: 1) the effects of a PE program for older adults with (suspected) ASD in terms of knowledge and recognition of ASD and traits, a better acceptance of the diagnosis,…
The primary objective of this study is to evaluate the (cost-)effectiveness of ET for late-life anxiety disorders delivered by trained MHNs in primary care, in terms of anxiety and quality of life, compared to UC. UC is not restricted, and the GP…
This clinical performance study/clinical investigation will evaluate the safety and effectiveness of GenDx CDx Tedopi in identifying HLA-A*02 status in metastatic NSCLC subjects who may be eligible for treatment with OSE2101.
rTMS is an intensive but effective treatment that could benefit from further optimization. Cognitive control training (CCT) engages the same underlying neural circuitry as rTMS and has been shown to improve therapeutic response (Koster et al., 2017…
To utilize the therascreen KRAS RGQ PCR Kit (KRAS Kit) as a screening test to identify KRAS G12C mutations in newly diagnosed metastatic NSCLC participants and thereby determine eligibility for enrolment into the Phase 3 clinical study (MK-1084-004…
The objective of this pilot study is to assess whether transportation of the sample via a pneumatic tube system (PTS) has any detrimental effects on the recovery of presepsin levels, when compared to traditional hand-delivery. This research will be…
Main objectives:a) examine and assess the (cost-)effectiveness of WHO's Doing What Matters in Times of Stress (DWM) in reducing psychological distress, improving mental health, and enhancing work-related well-being and…
We have recently implemented ultrarapid genetic testing using Nanopore long-read genome sequencing (LR-GS) at Erasmus MC to guide treatment and enhance outcomes in urgent care scenarios. In this study, we aim to retrospectively…
This mixed-methods pilot study will explore the effects of a group-based MBI on body and emotional awareness in TGD individuals by collecting both quantitative measures and qualitative experiences on an adapted gender-inclusive MBI program.&…
Through a randomized-controlled trial, we aim to investigate the effect of a growth mindset intervention for children with dyslexia on the effectiveness of their dyslexia treatment. Our primary hypothesis is that children who have received the…