31 results
The proportion of successful patients, defined as an improvement in LARS category, will be 25% larger in the experimental group than in the control group (in which 10 % improvement is assumed).
To evaluate the effectiveness of eccentric calf muscle exercise therapy compared to strength training of the upper extremities (control group) in patients with chronic midportion Achilles tendinopathy.
Most patients undergoing spine surgery with pedicle screw instrumentation will experience insufficient pain relief in the first three days after surgery, whereafter postoperative pain can be managed with conventional, non-opioid analgesics in most…
Renal artery denervation (RDN) on top of pulmonary vein isolation (PVI) will improve the success of ablative therapy for patients who have paroxysmal and/or persistent atrial fibrillation, with out of range hypertension (systolic >140 mmHg or…
The primary objective of this study is to determine patient perspective of and satisfaction with follow-up type and frequency after THA and TKA. Therefore, we will send surveys to patients who had a THA or TKA between 1 and 15 years ago.
Comparison of hearing preservation and outcome of two fundamentally different cochlear implants designs (LW or PM) and the two most used surgical approaches (RW or CO). Secondly, asses the structure preservation (i.e., scalar position) of each…
Does isolated cup revision surgery or liner exchange through the anterior approach result in increased functional status and higher patient satisfaction than through the posterolateral approach?
This intervention study investigates the effectiveness, costs and cost-effectiveness of a protein-enriched diet and resistance exercise training for 3 months on bone and muscle health, and quality of life in older adults recovering from an acute…
To evaluate the safety, feasibility and efficacy of an 8-week remotely supervised home-based maintenance exercise training program following pulmonary rehabilitation in patients with COPD.
The primary objective of the proposed research is to investigate in patients with PDD the efficacy of STN-DBS with best oral medical treatment (DBS-group) for disabling motor symptoms during off-drug phase compared to best oral medical treatment…
This project aims to investigate peripheral and central neuroplasticity following an early (<13 weeks after injury) and intensive (8 weeks of 6 hours of additional therapy) upper extremity motor training program (EIUMT)…
Phase 2 pilot-study: to examine feasible exercise dosages in patients with mCRC and collect data on preliminary effects on clinical outcomes.Phase 3 trial: to collect data on the efficacy of exercise on 1) chemotherapy dose modifications and 2)…
This study will determine whether there is a difference in disease free survival for patients treated with either a 1cm excision margin or 2cm margin for clinical stage II (pT2b-pT4b) primary cutaneous melanoma (AJCC 8th edition, Table 1). The…
The aim of this study is to reduce the need for colectomy and its* associated morbidity and mortality in patients with high-risk pT1 or low-risk pT2 colon carcinoma after endoscopic polypectomy by performing a (robot-assisted) laparoscopic wedge…
In this research, we are comparing two distinct physiotherapy treatments as post-operative care following shoulder arthroscopy (Bankart repair). Our aim is to gain a better understanding of how to provide optimal post-operative care for patients…
To study the human adult cochlea, in specific it's RNA and protein expression patterns and morphology.
The aim of the RADICES study is to investigate the effects of a 12-week exercise and nutrition intervention for patients with metastatic oesophageal or gastric cancer. The intervention will be completely tailored to the condition and nutritional…
Primary: To investigate the effect of a 4-week VR-exergame intervention on handgrip strength in patients staying in the ICU for 48 hours or longer compared to standard rehabilitation practices.Secondary: To investigate the longer term effect of a 4…
The goal of this study is to investigate which treatment(-s) lead to the best outcome by using existing variation of practice.
The aim of this study is to investigate the safety and efficacy of CAL-WR as primary and curative colon-preserving treatment for T1 colon cancer. Our primary endpoint is reduction of oncologic resections for low-risk T1 colon cancer. As secondary…