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Blind versus Ultrasound-guided Radius Reduction STudy

This multicentre randomised controlled trial aims to investigate whether PoCUS can be used as an adjunct to improve first attempt success rate in closed reductions of displaced distal radial fractures in adults in the ED.

THE USE STUDY Can Ultrasound Safely exclude Elbow fractures?

To establish the diagnostisch accuracy of ultrasound for the exclusion of fracture of the elbow

Fecal calprotectin guided referral strategy in children in primary care

Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.

Evaluation of different treatment thresholds in a clinical pathway for children with acute asthma

Evaluation of the effect of different treatment thresholds in a clinical pathway for children with acute asthma who are treated with supplemental oxygen

SIMBA study: Imaging study of Cognitive Outcomes after Treatment for Pediatric Brain Tumor

The primary objective is to examine relationships between neurocognitive performance and MRI parameters of brain vasculature, metabolism, and white matter diffusion in children who have been treated for posterior fossa tumor. Secondary objectives…

Single use vs reusable catheters in intermittent CatheterizatiOn for treatment of urinary retention: a Multicenter, Prospective, RandomizEd controlled, non-inferiority trial (COMPaRE)

The main objective of this trial is to determine whether reusable catheters are not less efficient as single use catheters, measured by symptomatic UTIs. Secondary objectives are adverse events like hospital admissions due to UTIs, urethral damage/…

Autonomous Blood Drawing Optimization and Performance Testing

This study has several objectives, in different (subsequent) study phases:• A1. Optimize and validate the technology of the VD to reach non-inferiority• B1. Demonstrate non-inferior performance and safety of the VD, for CE marking• B2. Demonstrate…

Personalized elective neck irradiation guided by sentinel lymph node biopsy in patients with squamous cell carcinoma of the oropharynx, larynx or hypopharynx with a clinically negative neck: (chemo)radiotherapy to the PRIMary tumor Only. The PRIMO study.

To compare safety and efficacy of treatment with sentinel lymph node biopsy guided elective neck irradiation versus standard elective neck irradiation in patients receiving definitive (chemo)radiotherapy for squamous cell carcinoma of the…

Leg Epilepsy Guard Study - LEGS

The purpose of this study is to determine whether a NightWatch worn on the leg detects the same seizures as a NightWatch worn on the arm. In addition, the signal quality of both devices will be examined.

BOOST - BMI of children with diabetes type 1: a study on the transition to smart technology

The objective is to investigate if AHCL in children with DM1 leads to a greater difference in BMI SDS compared to MDI. The second objective is to study if there is a difference between MDI and AHCL in DM1 regarding blood glucose regulation and…

Home-based treatment of dysfunctional breathing

To investigate the feasibility of treating pediatric patients with suspected dysfunctional breathing with the Glimp Pebbles.