141 results
The primary objective is to identify what causes colchicine resistance in FMF. Additionally, we will try to identify potential interventions to overcome resistance
A future project will focus on a new platform for at-home monitoring and testing of cochlear implants, developed by one of the manufacturers of cochlear implants, Advanced Bionics (AB). Their Research Application allows for clinicians to read out…
To compare the degree of osteoarthritis in the knee after 10 years, in patients with non-obstructive meniscal tear, between meniscal surgery and exercise therapy treatment.
To answer the following questions: 1. Who are the patients that need to be revaccinated?2. How many vaccinations are needed to restore SARS-CoV-2 immunity?3. Can the number of vaccinations needed to restore SARS-CoV-2 immunity be predicted?To…
Overall objective:To improve the existing drug prescribing and treatment monitoring process.Objective appendix 1: To prospectively evaluate the predictive performance of the MIPD strategy for tacrolimus and mycophenolic acid in paediatric patients…
The main study objectives include to:a. Use clinical and biological data to estimate the mean rates of change and the variability around the mean of clinical, digital, imaging, biological and genetic outcomes in study participants…
2 OBJECTIVES2.1 Primary Objective: To address the existing knowledge gaps and advance our understanding of cognitive variability, the CODEC study aims to integrate experience sampling methods, longitudinal designs, deep phenotyping cohorts, and…
Primary: To assess the effects of a 2-week preoperative vegan diet in comparison to an omnivorous diet on protein synthesis rates in Hoffa*s fat pad, synovium, bone, ligaments, menisci, and cartilage in older adults with knee osteoarthritis…
This study will consist of three parts with three different main objectives:- Part 1 - Pilot study; Primary objective: To assess and compare thermal comfort upon wearing a cooling vest, based on exposed cooling packs versus…
The prognostic accuracy of combining these four criteria to predict the later development of personality disorders (with/without psychosocial breakdown) is investigated in a longitudinal study. From this, a selection of items with the strongest…
Our aim is to develop JITAIs focused on behavioral activation (BA) for depression in close collaboration with patients and therapists, and to examine their usability, feasibility, and preliminary effectiveness.
This study is to investigate the safety and effectiveness of the AeriSeal system in limiting collateral ventilation within a target lung lobe. And to achieve lung volume reduction using Zephyur Vavles and assess lung function, hyperinflations and…
To generate a large, international Friedreich*s ataxia patient database (including healthy controls), alongside an integrated clinical and natural history database, which is linked to a biological samples and imaging repository, hereby creating a…
The primary objective of this study is to investigate the effect of dried chicory root (WholeFiber) during 6 weeks on fecal SCFA levels in intermediate to high-risk melanoma patients after surgical treatment with no concurrent adjuvant treatment.…
In this study we look at how long it takes for the levels of certain hormones and hormone-binding proteins to normalize discontinuation of COC use, in particular corticosteroid-binding globulin.
The current study describes the Antisocial High-Risk Cohort (i.e., WP3, a sub-project) of the larger Growing Up Together in Society Project (see appendix A), which has the aim to predict and understand behaviour that negatively affects society:…
Primary Objective: Assess the leakage of FFP2 respirators and surgical masks in human subjects using inhalable aerosols consisting of a solution of fluorescein in water. Secondary Objective(s): (a) Study the variability in total…
The primary objective is to examine the effect of twelve weeks supplementing daily one AstaPure® Oleoresin capsule on trans epidermal water loss (TEWL) in postmenopausal women. The secondary objectives are to investigate the effects on other skin,…
To acquire metabolic health data from three dietary challenge meals for thedevelopment of an algorithm for personalised dietary advice, and subsequentlytest the effectiveness of this personalised dietary advice compared to ageneral healthy diet…
Our study aims to identify unique Metabotypes among individuals with overweight at risk of T2DM and assess their response to a 1-year precision dietary macronutrient modulation. The objective is to provide proof-of-concept that this approach…