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An interventional, prospective IVD device study for the testing of DNA extracted from tumor tissue biopsy samples in a first line setting from patients diagnosed with metastatic Colorectal Cancer (mCRC) to determine the KRAS G12C mutation status as part of the inclusion criteria into the Amgen Phase III clinical trial (Protocol No 20210081) to demonstrate clinical performance of the therascreen® KRAS RGQ PCR Kit.

Approved WMORecruiting will start

To utilize the therascreen KRAS RGQ PCR Kit, as a screening test in Amgen*s Phase 3 Clinical Study Protocol 20210081, in order to identify patients with mCRC KRAS G12C mutation positive tumors to be enrolled in the drug clinical trial. Results of…

Effects of butyrate on depressive symptoms and affect in depression - a pilot randomized controlled trial

Approved WMORecruiting will start

The primary objectives are to study the feasibility and acceptability of an 8-week daily oral supplementation with tributyrin (4 g/day) - the triglyceride form of butyric acid - on top of treatment as usual (TAU) in adults (18 up to 65 years) with…