393 results
The objective is determine the correlation between the outcome of the cultures of the nasopharyngeal swab, the nose swab, the swab from a handkerchief and the handkerchief.
1. To establish whether serial exhaled breath analysis using eNose can detect invasive pulmonary aspergillosis in patients with prolonged chemotherapy induced neutropenia (neutrophil counts <0.5 x 10^9 for more than 7 days).2. To establish…
The main objective of this study is to assess the effects of rituximab (RTX) as a rescue therapy for therapy resistant progressive IMID- IP patients. Specifically there is an objective assessment of (1) pulmonary function tests (PFTs) and (2)…
The specific objectives are:1. What is the difference of in vitro CFTR function in CF patients with either mild (compound heterozygote A455E) mutations or severe (homozygote F508del) mutations with mild or severe clinical disease? 2. What is the…
To externally validate the accuracy of a host-response based diagnostics for differentiating between bacterial and viral etiology in pediatric patients aged 2 to 60 months with LRTI or FWS.
In the present study we want to examine the effect of salbutamol on the muscle tone of the diaphragm. We also want to examine the correlation between muscle tension measured by EMG and the Clinical Asthma Score. To include the children that come to…
The primary objective of the study is as follows:· To compare the rate of asthma exacerbations between patients with low baseline periostin levels (< 50 ng/mL) and patients with high baseline periostin levels (* 50 ng/mL), as measured by…
This study aims to investigate the feasability to use DW-MRI for mediastinal restaging after concomitant chemoradiotherapy and the feasabilitiy to predict whether or not mediastinal downstaging will be achieved during concomitant chemoradiotherapy…
To identify and define characteristics of healthy lymph nodes and lymph nodes involved in different pulmonal diseases (lungcancer and sarcoidosis)
Objective:The aim of our study is to obtain a collection of head and neck squamous cell carcinomas that is well characterized for relevant clinical parameters, including follow-up.
The purpose of this study is to determine the accuracy of the point-of-care IgE assay in atopic patients and healthy subjects. The POCT results will be compared to a reference immunoassay method for measuring this analyte.It intends to use this new…
1). To compare temporal fluctuations of lung function and inflammatory biomarkers in blood, nasal lavage, exhaled air and urine between patients with asthma and controls.2). To investigate the change in variations of these biomarkers upon…
To validate two less complex techniques, electrical activity of the diaphragm and ultrasound of the diaphragm, compared to the gold standard (transdiaphragmatic pressures) for monitoring diaphragm function and inspiratory effort during assisted MV…
The primary objective for this study is to compare the level and time course of the patient work-of-breathing during PS ventilation with the work-of-breathing during SIMV-PS ventilation with a lower rate of breaths per minute delivered by the…
pagina 7-8 protocol
To assess the accuracy and cost-effectiveness of PO screening for CCHD in the Dutch perinatal care system.
The primary objective is to assess the association between the EELV measured with RIP and EIT, and to graphically depict the changes in the pressure volume curve during stepwise decreasing the CDP in a recruited lung and correlate these with…
Single Ring Optical Catheter illumination study in patients with obstructive Sleep Apnea during DISE
Primary objective of the study is to create one or multiple light ring(s) in the upper airway of OSA patients by means of Single Ring Optical Catheter(s), visualize and record these light rings with a DISE endoscope, capture the change of light ring…
To describe the synchronicity of nIPPV respiratory support with spontaneous diaphragm activity and the effect of asynchrony of mechanical inflations and spontaneous breaths on lung volume, mechanical parameters and diaphragm activity in preterm…
To determine the true prevalence of pneumonia in exacerbating COPD patients by low-dose CT