1756 results
There are two objectives for this study: first, to find specific serum beta cell damage markers that can serve as a clinical predictive tool for beta cell allograft loss. Second, to compare quality of life and diabetes-related outcomes in patients…
The objective of the study is to investigate vertebral bone marrow fat fraction and bone mineral density during surgery induced weight loss.
The primary objective of this study is to investigate the relationship between diet composition, meal timing, and meal frequency with cognitive performance in nurses during a night shift setting.Secondary objectives of this study are 1) to…
The primary objective of this study is to evaluate the effect of inclisiran treatment on:•LDL-C levels at Day 510•Time adjusted percent change in LDL-C levels from baseline between Day 90 and Day 540 levels. The secondary objectives of this study…
First part of study (Phase 1)Aim: To evaluate the efficacy of ileal brake activation, by ingestion of an encapsulated nutrient mixture delivered to the stomach (placebo) or distal small intestine (active) analysed by the amount of food consumed…
The primary objective of this study is to evaluate the effect of inclisiran treatment on:*LDL-C levels at Day 510*Time adjusted percent change in LDL-C levels from baseline between Day 90 and Day 540 levelsThe secondary objectives of this study are…
To investigate different dosages of 4 weeks oral Eubacterium hallii treatment on safety and efficacy parameters.
Primary objective To assess accuracy of GCCGM vs FLFM in 18 subjects with diabetes during a 6 day mountainbike tour in the AlpsSecondary objectives To assess the (differences in ) time in hypo-, normo- ,and hyperglycemia (expressed in minutes per…
The purpose of the study is to investigate the effect of (repeated) cast immobilization on the bone strength of the lower leg in patients with diabetes mellitus. In this study, bone strength is examined by cortex thickness in millimeters and density…
To investigate whether STG enhances BAT activation, thereby increasing energy expenditure and combustion of TG-derived fatty acids, resulting in lowering of plasma TG levels and body weight.
In this study we aim to investigate the presence of CAN in diabetic patients scheduled for elective major abdominal and thoracic surgery and its relation with perioperative hemodynamic changes.
Primary :To compare diet quality and nutrient status before and during pregnancy of women who develop GDM with those who have normal blood sugar levelsSecondary:*To compare body composition before (and during) pregnancy of women who develop GDM with…
To investigate the impact of (a disrupted) circadian rhythm on food preferences and chemosensory perception.
This research project aims to determine the feasibility of setting up a randomized controlled trial to study the effects of different fluid management protocols on the outcome of mechanically ventilated pediatric patients with acute infectious lung…
To assess the acute (2h) and short term (2 days and 4 week) effects of daily administration of 5g of NWT03 (an egg-protein hydrolysate) on carotid-radial Pulse Wave Velocity (cr-PWV). Secondary objectives are to assess its effects on carotid-femoral…
To describe the wound related complication rate in post-bariatric body contouring surgery patients who are treated according to a new guideline and assess the factors associated with a higher complication rate.
PrimaryThe 3 months* effect of Vildagliptin on insulin synthesis and storage capacitySecondaryThe 3 months* effect of vildagliptin on- Glucose, insulin, C-peptide levels- Hormonal axes, most importantly GLP1 and GIP and Glucagon- Body weight, body…
To evaluate the difference in the post fat load non HDL after an oral fatload between bezafibrate and placebo in patients with FD using standard lipid-lowering therapy
To assess the efficacy of a TCC, a BTCC and a cast shoe with similar plantar soles on offloading the previous ulcer location in people with DM and peripheral neuropathy.
- To determine whether there is a mitigated immediate immune response to islet infusion in immunosuppressed recipients- To determine if complement activation during immediate immune response is affected in immunocompromised recipients