43 results
Primary Objectives:• show effectiveness of the SMSC instrument in 3D correction of the spine prior to placement of the implants.The hypothesis is that to achieve de-rotation of the spine without failure of the pedicle screws, de-rotation has to be…
Documentation of the patients' functional recovery and quantification of fusion after implantation of 3-D trabecular titanium cages on the short and long term. These data will be compared with the recently performed randomized CASCADE trial on…
The aim of this study is to compare the effects of anterior cervical discectomy versus percutaneous plasma discectomy on pain, on global perceived effect, functional status and health-related quality of life in a group of patients with cervical…
This study is designed to evaluate the effectiveness and safety of the MID-C System.
The objectives of this study are to evaluate the safety and performance of the Cadisc*-C Total Cervical Disc Replacement Device in the surgical replacement of the cervical intervertebral discs (C3 to C7) for patients requiring surgical intervention…
Assessing the effectiveness and safety of parecoxib compared to placebo in pain relief children undergoing scoliosis surgery
The primary objective is to gain insight into the effects of guided imagery on pain intensity in people with fibromyalgia. Secondary objective is to gain insight into the effects on self efficacy and functional status.
Our primary study objective is whether visualizing and scoring of emboli is technically feasible. Secondary we want to asses the occurence and incidence of embolic events during spinal instrumentation surgery by intraoperative monitoring with TEE.…
To assess if a continued rehabilitation program in the first six weeks post-surgery for patients following a first time is morecost-effective as compared to no further treatment after discharge from the hospital an economic evaluation alongside…
In the literature the effectiveness of the anterior cervical discectomy is measured using subjective validated questionnaires.It would be an important improvement if it is possible to detect the inflammatory process of the dorsal root ganglion with…
To compare functional recovery of the patient and the fusion status of ceramic cages versus PEEK cages on the short and long term.
(1) To phenotype chronic low back pain patients in terms of endogenous modulation of pain, central sensitization/facilitation, and the presence of a neuropathic pain component;(2) To assess the effect of a three-month treatment with tapentadol on…
The main objective is to gain insight into the effects of guided imagery on pain, self efficacy and functional status of people with fibromyalgia and into the relationships between these outcome variables.
The objectives of this study are to evaluate the safety and performance of the CAdisc*-L Total Lumbar Disc Replacement Device in the surgical replacement of the lumbar intervertebral discs (L3 to S1) for patients requiring surgical intervention for…
The purpose of our study is to evaluate modern dual-energy x-ray absorptiometry scan techniques (iDEXA; General Electronics, USA) as an adjunctive diagnostic tool to evaluate the ongoing process of spinal fusion. Changes in bone mineral density (BMD…
- To systematically determine the influence of disease activity of RA on the metabolic syndrome of patients with chronic RA (disease duration > 2 years).
To assess the analgesic efficacy, safety, and tolerability of once daily orally administered GRT6005 in a total of 3 fixed doses (i.e., 200 µg, 400 µg, and 600 µg GRT6005) compared to placebo in subjects with moderate to severe chronic LBP.
A study on extent-related outcome and complications for degenerative cervical spinal disease has not yet been performed. Results of this study may form the basis for a guideline regarding the extent of fixation in degenerative cervical spinal…
1. To compare the efficacy of tofacitinib, in doses of 2 mg, 5 mg, and 10 mg BID versus placebo on the ASAS20 response rate at Week 12 in subjects with active AS that have had an inadequate response to previous treatment.2. To estimate the placebo-…
To evaluate the (cost)effectiveness of a classification algorithm, based on patient*s symptoms andclinical presentation, that directs patients with non specific LBP to the therapy (exercise therapy ormanual therapy) that they are most likely to…