89 results
• Compare bone density between patients with mild haemophilic and those with severe haemophilia*.• Compare the relationship between treatment regimen: prophylactic (high-dose vs. intermediate dose) and on-demand and bone density.• Examine the…
The primary objective in the glucocorticoid-continuing subpopulation of men and women treated with chronic glucocorticoid therapy (>= 7.5 mg daily prednisone or its equivalent for >= 3 months and are planning to continue treatment for…
The objective of the study is to investigate vertebral bone marrow fat fraction and bone mineral density during surgery induced weight loss.
The purpose of the study is to investigate the effect of (repeated) cast immobilization on the bone strength of the lower leg in patients with diabetes mellitus. In this study, bone strength is examined by cortex thickness in millimeters and density…
What is the most optimal treatment strategy for children / adolescents with knee complaints? Our hypothesis is (based on the invasive surgical procedure) patients that will be surgical treated (index group) have a clinical relevant gain of pain…
To assess the effect of AMG785 treatment for 12 months followed by alendronate treatment compared with alendronate on the incidence of clinical fracture and new vertebral fracture.
Our aim is to study whether the pain response after three months in patients with bone metastatic disease increases after SBRT in comparison to low dose EBRT.
Effect on bone mineral density.
To determine the efficacy and safety of PREOB®, a proprietary population of autologous bone-forming cells, in the treatment of early stage non-traumatic osteonecrosis of the femoral head.
The primary objective of this study is:* The primary objective of this clinical trial will be to determine the efficacy of MMB compared with ruxolitinib as measured by splenic response rate at Week 24 (SRR24).The secondary objectives of this study…
Primary Objective: - Determine the effectiveness of a treatment with pulsed electromagnetic field therapy in patients with medial tibial stress syndrome (MTSS).Secondary Objective(s): - Determine the feasibility of the study design.- Determine the…
> Primary Objective:This is a pilot study, aiming at the clinical evaluation with respect to safety and feasibility of a one-step surgical procedure for maxillary sinus floor augmentation for the placement of dental implants, using a ceramic…
To investigate the differences in facial analysis, between patients with acromegaly, being in remission, and healthy subjects, and to investigate the changes in relational proportions between these facial structures.
Evaluation of the effect of postoperative physiotherapy, after Chevron osteotomy, on foot function.
To investigate in vivo whether a measurable increase in systemic ATP levels occurs in response to mechanical stimulation of bone in humans.
To determine the incidence of vertebral fractures and exploring riscfactors in the geriatric outpatients.The effect of new vertebral fractures on daily activities, quality of life, reported falls.To explore the relation between frailty syndrome…
The aims of the present study are 1) to confirm the high prevalence of dRTA in Sjögren using the urinary acidification test with ammonium chloride, 2) to determine the prevalence of disorders in calcium metabolism in pSS patients with dRTA, 3) to…
The objective of the study is to study the effect of Teripratide (rhPTH 1-34) on undercarboxylated osteocalcin levels, testosterone concentrations, glucose tolerance and insulin sensitivity and changes in body composition in male subjects with…
To study the inflammatory response (induration) to intracutaneous Candida albicans in healthy individuals, patients with diabetes without polyneuropathy, patients with diabetic polyneuropathy and patients with a history of Charcot neuro-…
The objective is to study the effect of beta-agonist and beta-antagonist treatment on human bone remodeling.