192 results
To study the effects of ARA290 on the cognitive and neural processing of emotions in healthy volunteers 7 days post-administration.
The aim of this study is to investigate the effectiveness of EMDR with traumatized adolescents (12-18 years) with major depressive disorder.
To investigate whether bright light therapy is an effective treatment for depression during pregnancy compared with low-intensity placebo light therapy (proof-of-principle) and to investigate the late effects of bright light therapy versus placebo…
The primary objective is to determine the efficacy of a disease specific cognitive behavioral therapy program in adolescents with IBD and increased symptoms of depression or anxiety on reducing symptoms of depression. Secondary objectives are to…
To investigate the effect of JNJ-42847922 given as monotherapy as compared to placebo on symptoms of depression in male and female MDD patients
The main objective of the study is to investigate whether a 9 week MFT for adolescents with ASD and clinically elevated internalizing symptoms, reduces adolescent's internalizing symptoms. Secondary objective is to investigate the process of…
(1) To investigate the effect of rTMS in a treatment set-up of 4 weeks including sham-rTMSas a control in 2 x 50 patients who have had at least two prior antidepressant therapies and psychotherapy according to the Dutch guideline of depression.(2)…
Primary Objective- To assess short and long-term effects of individual Cognitive Behavioral Therapy (CBT) and individual Mindfulness-Based Cognitive Therapy (MBCT) in reducing depressive symptoms in cancer patients with clinically significant…
The effectiveness of psychotherapy can be improved by increasing the frequency of sessions at the beginning of therapy. In addition, understanding processes that account for therapeutic change might enable us to optimize treatments.
Compare the clinical- and cost-effectiveness of blended cognitive behavioral treatment (bCBT) to treatment as usual (TAU) for adults with MDD in specialised ambulatory mental healthcare.
To examine whether adding yoga-based therapy (YBT) to treatment as usual (TAU) for young women with MDD leads to (1) greater reductions in symptoms and (2) greater cost-effectiveness in that the economic benefits of adding YBT to TAU outweigh the…
The primary objective of the present pilot study is: 1. To evaluate the temporal dynamics between neurofeedback parameters and depressive symptoms in older persons suffering from clinically relevant depressive symptoms. The secondary objectives are:…
(1) To investigate the efficacy of LT in patients with T2DM and comorbid depression, and (2) whether LT leads to improved insulin sensitivity, and (3) whether effects on mood and metabolic control are mediated by restoration of the circadian…
Cost effectiveness of augmented cognitive behavioural therapy for post stroke depression and anxiety
Our main objective is to investigate whether an augmented CBT leads to the reduction of depression and anxiety symptoms in stroke patients. We will compare the outcomes of this experimental treatment with a control intervention (i.e., computerized…
The present study is aimed at investigating cognitive underpinnings of depression, by focusing on working memory abilities in both depressed and non-depressed individuals. These findings will be employed to design and test a therapeutic intervention…
The aim of this study is to investigate the effectiveness and the cost-effectiveness of the individual CBT program the *D(o)epressie cursus* by means of the following hypotheses;1. Is the individual CBT program the *D(o)epressie cursus* more…
The primary objective of this trial is to determine the clinical and cost effectiveness of computerized cognitive behavioural therapy with therapist support, compared to face-to face therapy based on cognitive-behavioural techniques for mild to…
The objective of the study is to gain preliminary insight in the efficacy of MBCT in the prevention of recurrence of depression in SAD patients.
To compare cerebral activity patterns during emotional and cognitive processing among patients with post-MI depression and patients with regular depression.
- to evaluate the safety and tolerability of BCI-838 following oral administration of single doses of BCI-838 in healthy male subjects- to determine the pharmacokinetics of BCI-838 and metabolite BCI-632 following oral administration of single…